List of publication

[ 発 表 論 文 ]

原著論文  ―Original articles―

2022

  1. K. Suzuki,Y. Yoshizaki, K. Horii, N. Murase, A. Kuzuya, Y. Ohya, Preparation of hyaluronic acid-coated polymeric micelles for nasal vaccine delivery, Biomater. Sci., 10, 1920-1928 (2022.1).
  2. T. Yokoi, A. Kuzuya, T. Nakajima, T. Kurokawa, J. P. Gong, Y. Ohya, Synthesis of degradable double network gels using a hydrolysable cross-linker, Polym. Chem., in press.

2021

  1. Y. Yoshizaki, T. Nagata, S. Fujiwara, S. Takai, D. Jin, A. Kuzuya, Y. Ohya*, Postoperative Adhesion Prevention Using a Biodegradable Temperature-responsive Injectable Polymer System and Concomitant Effects of Chymase Inhibitor, ACS Appl. Bio Mater. 4(4), 3079-3088 (2021.4). https://pubs.acs.org/doi/10.1021/acsabm.0c01467
  2.  Y. Yoshizaki, H. Takai, N. Mayumi, S. Fujiwara, A. Kuzuya, Y. Ohya*, Cellular Therapy for Myocardial Ischemia Using a Temperature-responsive Biodegradable Injectable Polymer System with Adipose-derived Stem Cells, Sci. Technol. Adv. Mater.,22(1). 627-642 (2021.8). https://doi.org/10.1080/14686996.2021.1938212
  3. S. Fujiwara, Y. Yoshizaki, A. Kuzuya, Y. Ohya*, Temperature-Responsive Biodegradable Injectable Polymers with Tissue Adhesive Properties, Acta Biomater., 135, 318-330 (2021.11). https://doi.org/10.1016/j.actbio.2021.08.033

2020

  1. H. Tsuji, S. Sato, N. Masaki, Y. Arakawa, Y. Yoshizaki, A. Kuzuya, Y. Ohya, Thermal Properties and Degradation of Enantiomeric Copolyesteramides Poly(lactic acid-co-alanine)s, Polym. Degrad. Stab., 171, 109047 (2020.1). doi: 10.1016/j.polymdegradstab.2019.109047
  2. H. Tsuji, S. Sato, N. Masaki, Y. Arakawa, Y. Yoshizaki, A. Kuzuya, Y. Ohya, Stereocomplex Crystallization and Homo-Crystallization of Enantiomeric Copolyesteramides Poly(lactic acid-co-alanine)s from the Melt, Polym. Crystalli., 3(2), e10094 (2020.4). DOI:10.1002/pcr2.10094
  3. Y. Yoshizaki, H. Yamamoto, A Kuzuya, Y. Ohya, Sustained Drug-releasing Systems Using Temperature-responsive Injectable Polymers Containing Liposomes, ACS Symp. Ser., 1350, 35-45 (2020.5). ISBN13: 9780841238145, eISBN: 9780841298996, DOI: 10.1021/bk-2020-1350
  4. Y. Ohya, *K. Nishimura, H. Sumida, Y. Yoshizaki, A. Kuzuya, A. Mahara, T. Yamaoka,* Cellular Attachment Behavior on Biodegradable Polymer Surface Immobilizing Endothelial Cell-Specific Peptide, J. Biomat. Sci. Polym. Ed., 31(11), 1475-1488(2020.5). DOI: 10.1080/09205063.2020.1762325
  5. A. Mahara, M. Li, Y. Ohya, T. Yamaoka, Small-Diameter Synthetic Vascular Graft Immobilized with the REDV Peptide Reduces Early-Stage Fibrin Clot Deposition and Results in Graft Patency in Rats, Biomacromolecules, 21(8), 3092-3101 (2020.8). https://doi.org/10.1021/acs.biomac.0c00457
  6. H. Sumida, Y. Yoshizaki, A. Kuzuya, Y. Ohya, Versatile Cell-Specific Ligand Arrangement System onto Desired Compartments of Biodegradable Matrices for Site-Selective Cell Adhesion Using DNA Tags, Biomacromolecules 2020, 21 (9), 3713-3723 (2020.9). http://dx.doi.org/10.1021/acs.biomac.0c00814.
  7. A. Mahara, M. Kitai, H. Masunaga, T. Hikima, Y. Ohya, S. Sasaki, S. Sakurai, T. Yamaoka*, Modification of decellularized vascular xenografts with 8-arm polyethylene glycol suppresses macrophage infiltration but maintains graft degradability, J. Biomed. Mater. Res. Part A, 108(10), 2005-2014 (2020.10). http://dx.doi.org/10.1002/jbm.a.36960

2019

  1. S. Tanaka, S. K. Chan, T. S. Lim, Y. Ohya, A. Kuzuya, DNA Quadruplex Hydrogel Beads Showing Peroxidase Activity, J. Electrochem. Soc., 166(9), B3271-B3273 (2019.5).
  2. K. Matsuda, Arif Md. Rashedul Kabir, N. Akamatsu, A. Saito, S. Ishikawa, T. Matsuyama, O. Ditzer, Md. Sirajul Islam, Y. Ohya, K. Sada, A. Konagaya, A. Kuzuya, and A. Kakugo, Artificial Smooth Muscle Model Composed of Hierarchically Ordered Microtubule Asters Mediated by DNA Origami Nanostructures, Nano Lett., 19(6), 3933-3938 (2019.6). DOI: 10.1021/acs.nanolett.9b01201
  3. S. Tanaka, S. Yukami, Y. Ohya, A. Kuzuya, Cell Culture on/in DNA Quadruplex Hydrogels Made of Polyethylene Glycol-Oligodeoxynucleotide Conjugates, Polymers., 11, 1607(2019.10). DOI: 10.3390/polym11101607

2018

  1. H. Tsuji, S. Sato, N. Masaki, Y. Arakawa, A. Kuzuya, Y. Ohya, Stereocomplex Crystallization and Homo-Crystallization of Enantiomeric Poly(lactic acid-co-alanine)s with Ester and Amide Linkages, Polym. Chem., 9(5), 565-575 (2018.2).
  2. S. Tanaka, S. Yukami, K. Fukushima, K. Wakabayashi, Y. Ohya, and A. Kuzuya, Bulk pH-Responsive DNA Quadruplex Hydrogels Prepared by Liquid-Phase, Large-Scale DNA Synthesis, ACS Macro Lett., 7, 295–299(2018.2). DOI: 10.1021/acsmacrolett.8b00063.
  3. Y. Ohya, A. Takahashi, A. Kuzuya, Preparation of Biodegradable Oligo(lactide)s-Grafted Dextran Nanogels for Efficient Drug Delivery by Controlling Intracellular Traffic, Int. J. Mol. Sci., 19, 1606(2018.5). DOI: 10.3390/ijms19061606.

2017

  1. Y. Yoshida, K. Kawahara, K. Inamoto, S. Mitsumune, S. Ichikawa, A Kuzuya, Y. Ohya, Biodegradable Injectable Polymer Systems Exhibiting Temperature-Responsive Irreversible Sol-to-Gel Transition by Covalent Bond Formation, ACS Biomater. Sci. Eng., 3, 56-67 (2017). 10.1021/acsbiomaterials.6b00581.
  2. Y. Ohya, A. Takahashi, H. Takaishi, A Kuzuya, Synthesis and Temperature-responsiveness of Poly(ethylene glycol)-like Biodegradable Poly(ether-ester)s, ACS Symp. Ser., 1253, 93-104 (2017). (Advances in Bioinspired and Biomedical Materials Vol. 2, Chapter 5) 10.1021/bk-2017-1253.ch005.
  3. Y. Yoshida, K. Kawahara, S. Mitsumune, A Kuzuya, Y. Ohya, Injectable and Biodegradable Temperature-responsive Mixed Polymer Systems Providing Variable Gel-forming pH Regions, J. Biomat. Sci. Polym., Ed., 28, 1158-1171 (2017).
  4. Y. Yoshida, H. Takai, K. Kawahara, S. Mitsumune, K. Takata, A Kuzuya, Y. Ohya, Biodegradable Injectable Polymer Systems Exhibiting Longer and Controllable Duration Time of the Gel State, Biomat. Sci., 5, 1304-1314 (2017).
  5. Y. Yoshida, K. Takata, H. Takai, K. Kawahara, A Kuzuya, Y. Ohya, Extemporaneously Preparative Biodegradable Injectable Polymer Systems Exhibiting Temperature-Responsive Irreversible Gelation, J. Biomat. Sci. Polym. Ed., 28, 1427-1443 (2017).
  6. K. Takata, K. Kawahara, Y. Yoshida, A Kuzuya, Y. Ohya, Analysis of the sol-to-gel transition behavior of temperature-responsive injectable polymer systems by fluorescence resonance energy transfer, Polym. J., 49, 677-684 (2017).
  7. A. Kuzuya, Y. Sakai, Y. Xu, Y. Yamanaka, , Y. Ohya, M. Komiyama, Allosteric Control of Nanomechanical DNA Origami Pinching Devices for Enhanced Target Binding, Chem. Commun., 53, 8276-8279 (2017).
  8. S. Tanaka, K. Wakabayashi, K. Fukushima, S. Yukami, R. Maezawa, Y. Takeda, K.Tatsumi, Y. Ohya, A. Kuzuya*, Intelligent, Biodegradable, and Self-Healing Hydrogels Utilizing DNA Quadruplexes, Chem. Asian J., 12, 2388-2392 (2017).
  9. K. Takata, H. Takai, Y. Yoshizaki, T. Nagata, K. Kawahara, Y. Yoshida, A. Kuzuya, Y. Ohya, Peptide drug release behavior from biodegradable temperature-responsive injectable hydrogels exhibiting irreversible gelation, Gels., 3(4), 38 (2017.10). doi: 10.3390/gels3040038.

2016

  1. H. Tsuji, K. Tamai, T. Kimura, A. Kubota, A. Takahashi, A. Kuzuya, Y. Ohya, Stereocomplex- and Homo-Crystallization of Blends from 2-Armed Poly(L-lactide) and Poly(D-lactide) with Identical and Opposite Chain Directional Architectures and of 2-Armed Stereo Diblock Poly(lactide), Polymer, 96, 167-181 (2016.5). 10.1016/j.polymer.2016.04.049.

2015

  1. A. Kuzuya, M. Kaino, M. Hashizume, K. Matsumoto, T. Uehara, Y. Matsuo, H. Mitomo, K. Niikura, K. Ijiro, Y. Ohya, Encapsulation of a gold nanoparticle in a DNA origami container, Polym. J., 47, 177-182 (2015.2).
  2. Y. Han, A. Hara, A. Kuzuya, R. Watanabe, Y. Ohya, A. Konagaya, Automatic Recognition of DNA Pliers in Atomic Force Microscopy Images, New Generation Computing, 33(3) 253-270, (2015.7).

2014

  1. A. Kuzuya, R. Watanabe, M. Hashizume, M. Kaino, S. Minamida, K. Kameda, Y. Ohya, Precise Structure Control of Three-State Nanomechanical DNA Origami Devices, Methods, 67, 250-255 (2014). (doi: dx.doi.org/10.1016/j.ymeth.2013.11.003).
  2. A. Takahashi, M. Umezaki, Y. Yoshida, A. Kuzuya, Y. Ohya, The Effects of Molecular Structure on Sol-to-gel Transition of Biodegradable Poly(depsipeptide-co-lactide)-g-PEG Copolymers, J. Biomat. Sci. Polym, Ed., 25(5), 444-454 (2014.4).
  3. A. Takahashi, Y. Ozaki, A. Kuzuya, Y. Ohya, Impact of Core-forming Segment Structure on Drug Loading in Biodegradable Polymeric Micelles Using PEG-b-Poly(lactide-co-depsipeptide) Block Copolymers, BioMed Res. Int., 2014, Article ID 579212, 10 pages.
  4. A. Takahashi, M. Umezaki, Y. Yoshida, A. Kuzuya, Y. Ohya, A Macromolecular Prodrug-type Injectable Polymer Composed of Poly(depsipeptide-co-lactide)-g-PEG for Sustained Release of Drugs, Polym. Adv. Technol., 25, 1226-1233(2014). 10.1002/pat.3265.
  5. Y. Yoshida, A. Takahashi, A. Kuzuya, Y. Ohya, Instant Preparation of Formulation for Biodegradable Injectable Polymers Exhibiting Temperature-responsive Sol-gel Transition, Polym. J., 46, 632-635 (2014.9). 10.1038/pj.2014.30.
  6. Y. Ohya, J. Matori, T. Ouchi, Preparation of Growth Factor-Loaded Biodegradable Matrices Consisting of Poly(depsipeptide-co-lactide) and Cell Growth on the Matrices, React. Funct. Polym., 81, 33-39 (2014).
  7. T. Kimura, A. Okuno, Y. Ohya, A. Kishida, Assembly of Poly(vinyl alcohol) and DNA via Hydrogen Bonds Induced by High Hydrostatic Pressurization, Sensors and Materials, 26(8), 607-614 (2014).
  8. A. Kuzuya, R. Watanabe, Y. Yamanaka, T. Tamaki, M. Kaino, Y. Ohya, Nanomechanical DNA Origami pH Sensors, Sensors, 14(10), 19329-19335 (2014). doi:10.3390/s141019329.

2013

  1. K. Nagahama, R. Aoki, T. Saito, T. Ouchi, Y. Ohya, N. Yui, Enhanced Stereocomplex Formation of Enantiomeric Polylactides Grafted on a Polyrotaxane Platform, Polym. Chem., 4, 1769-1773 (2013).

2012

  1. K. Nagahama, K. Shimizu, S. Ichimura, A. Takahashi, T. Ouchi, Y. Ohya*, Biodegradable Stereocomplex Materials of Polylactide-grafted Dextran Exhibiting Soft and Tough Properties in Dry and Wet States, J. Polym. Sci. Part A Polym. Chem., 50, 2669-2676 (2012).
  2. Y. Ohya, N. Miyoshi, M. Hashizume, T. Tamaki, T. Uehara, S. Shingubara, A. Kuzuya, Formation of 1D and 2D Gold Nanoparticle Arrays by Divalent DNA-Gold Nanoparticle Conjugates, Small,28, 2335-2340 (2012). (Selected as Back Cover)
  3. T. Yamazaki, Y. Aiba, K. Yasuda, Y. Sakai, Y. Yamanaka, A. Kuzuya, Y. Ohya, M. Komiyama, Clear-cut Observation of PNA Invasion using Nanomechanical DNA Origami Devices, Chem. Commun.,48, 11361-11363 (2012).(DOI: 10.1039/C2CC36358E)

2011

  1. K. Nagahama, T. Saito, T. Ouchi, Y. Ohya, Biodegradable Nano-Aggregates of Star-Shaped 8-arm PEG-PLLA Block Copolymers for Encapsulation of Water-Soluble Macromolecules, J. Biomat. Sci. Polym. Ed., 22(1-3), 407-116 (2011).
  2. Y. Ohya, S. Takeda, Y. Shibata, T. Ouchi, A. Kano, T. Iwata, S. Mochizuki, Y. Taniwaki, A. Maruyama, Evaluation of Polyanion-Coated Biodegradable Polymeric Micelles as Drug Delivery Vehicles, J. Contr. Rel., 155(1), 104-110 (2011).

2010

  1. K. Nagahama, J. Ohmura, H. Sakaue, T. Ouchi, Y. Ohya, N. Yui, Preparation of Nano-aggregates through Self-assembly of Amphiphilic Polyrotaxane Composed of PLLA-PEG-PLLA Triblock Copolymer and α-Cyclodextrins, Chem. Lett., 39,250-251 (2010).
  2. Y. Ohya, S. Takeda, Y. Shibata, T. Ouchi, A. Maruyama, Preparation of Biodegradable Polymer Micelles Exhibiting High Stability by Coating with Polyion Complex, Macromol. Chem. Phys., 211(16), 1750-1756 (2010).(Selected as Back Cover)
  3. T. Tamaki, N. Miyoshi, T. Uehara, Y. Ohya, Isolation of Gold Nanoparticle/Oligo-DNA Conjugates by the Number of Oligo-DNAs Attached and Their Formation of Self-assembly, Chem. Lett., 39(10), 1084-1085 (2010).
  4. K. Nagahama, T. Saito, T. Ouchi, Y. Ohya, Biodegradable Nano-Aggregates of Star-Shaped 8-arm PEG-PLLA Block Copolymers for Encapsulation of Water-Soluble Macromolecules, J. Biomat. Sci. Polym. Ed., 22(1-3), 407-116 (in press.

2009

  1. Y. Ohya, T. Nohori, T. Nishi, S. Jo, T. Ouchi, Polyassembly Formation of Complementary Half-sliding Oligo-DNAs and the Atomic Force Microscopic Observation, J. Nanosci. Nanotechnol., 9(1), 313-317 (2009).
  2. Y. Ohya, N. Hashimoto, S. Jo, T. Nohori, T. Yoshikuni, T. Ouchi, H. Tamiaki, Synthesis of Oligo-DNA Containing Hydrophilic Porphyrin in the Main Chain, and Its Energy Transfer Behavior in Duplex State, Supramol. Chem., 21(3-4), 301-309 (2009).
  3. Y. Ohya, H. Yamamoto, K. Nagahama, T. Ouchi, Effects of Polydepsipeptide Side-Chain Groups on the Temperature Sensitivity of Triblock Copolymers Composed of Polydepsipeptides and Poly(ethylene glycol), J. Polym. Sci. Part A Polym. Chem., 47(15), 3892-3903 (2009).
  4. K. Nagahama, Y. Ueda, T. Ouchi, Y. Ohya, Biodegradable Shape-Memory Polymers Exhibiting Sharp Thermal Transitions and Controlled Drug Release, Biomacromolecules, 10(7), 1789-1794 (2009).
  5. K. Nagahama, M. Hashizume, H. Yamamoto, T. Ouchi, Y. Ohya, Hydrophobically Modified Biodegradable Poly(ethylene glycol) Copolymers that Form Temperature-Responsive Nanogels, Langmuir, 25(17), 9734-9740 (2009).
  6. K. Nagahama, Y. Imai, T. Nakayama, J. Ohmura T. Ouchi, Y. Ohya, Thermo-Sensitive Sol-Gel Transition of Poly(depsipeptide-co-lactide)-g-PEG Copolymers in Aqueous Solution, Polymer, 50(14), 3547-3555 (2009).
  7. Y. Ohya, S. Takamido, K. Nagahama, T. Ouchi, R. Katoono, N. Yui, Polyrotaxane Composed of Poly-L-Lactide and α-Cyclodextrin Exhibiting Protease-Triggered Hydrolysis, Biomacromolecules, 10(8), 2261-2267 (2009).
  8. K. Nagahama, K. Shimizu, T. Ouchi, Y. Ohya, Biodegradable Poly(L-lactide)-Grafted α-Cyclodextrin Copolymer Displaying Specific Dye Absorption by Host-Guest Interactions, React. Funct. Polym., 69(12),891-897 (2009).

2008

  1. K. Nagahama, T. Ouchi, Y. Ohya, Temperature-Induced Hydrogel through Self-Assembly of Cholesterol-Substituted Star PEG-b-PLLA Copolymers as an Injectable Scaffold for Tissue Engineering, Adv. Funct. Mater., 18(8), 1220-1231 (2008).
  2. K. Nagahama, K. Fujiura, S. Enami, T. Ouchi, Y. Ohya, Irreversible Temperature-Responsive Formation of High-strength Hydrogel from an Enantiomeric Mixture of Starburst Triblock Copolymers Consisting of 8-arm PEG and PLLA or PDLA, J. Polym. Sci. Part A Polym. Chem., 46(18), 6317-6332 (2008).
  3. K. Nagahama, T. Ouchi, Y. Ohya, Biodegradable Nanogels Prepared by Self-Assembly of Poly(L-Lactide)-Grafted Dextran: Entrapment and Release of Protein, Macromol. Biosci., 8(11), 1044-1952 (2008).

2007

  1. K. Nagahama, Y. Nishimura, Y. Ohya, T. Ouchi, Impacts of Stereoregularity and Stereocomplex Formation on Physicochemical, Protein Adsorption and Cell Adhesion Behaviors of Star-Shaped 8-Arms Poly(ethylene glycol)-Poly(lactide) Block Copolymer Films, Polymer, 48(9), 2649-2658 (2007).
  2. K. Nagahama, Y. Mori Y. Ohya, T. Ouchi, Biodegradable Nanogel Formation of Polylactide-Grafted Dextran Copolymer in Dilute Aqueous Solution and Enhancement of Its Stability by Stereocomplexation, Biomacromolecules, 8(7), 2135-2141 (2007).
  3. Y. Ohya, S. Takamido, K. Nagahama, T. Ouchi, T. Ooya, R. Katoono, N. Yui, Molecular “Screw and Nut”: α-Cyclodextrin Recognizes Polylactide Chirality, Macromolecules, 40(18), 6441-6444 (2007).
  4. K. Nagahama, Y. Ueda, T. Ouchi, Y. Ohya, Exhibition of Soft and Tenacious Characters Based on Liquid Crystal Formation by Introduction of Cholesterol Groups on Biodegradable Lactide Copolymer, Biomacromolecules, 8(12), 3938-3943 (2007).

2006

  1. T. Ouchi, S. Ichimura, Y. Ohya, Synthesis of Branched Poly(lactide) Using Polyglycidol and Thermal, Mechanical Properties of Its Solution-cast Film, Polymer, 47(1), 429-434 (2006).
  2. K. Nagahama, Y. Ohya, T. Ouchi, The Suppression of Cell and Platelet Adhesion to Star-Shaped Poly(ethylene glycol)-Poly(L-lacitde) Block Copolymer Film, Macromol. Biosci., 6(6), 412-419 (2006).
  3. K. Nagahama, Y. Ohya, T. Ouchi, Synthesis of Star-Shaped 8arms Poly(ethylene glycol)-Poly(L-lacitde) Block Copolymer and Physical Properties of Its Solution Cast Film as Soft Biomaterial, Polym. J., 38(8), 852-860 (2006).
  4. Y. Ohya, T. Nakai, K. Nagahama, T. Ouchi, S. Tanaka, K. Kato, The Synthesis and Biodegradability of Poly(lactide-random-depsipeptide)-PEG-Poly(lactide-random-depsipeptide) ABA-type Triblock Copolymers, J. Bioact. Compat. Polym., 21(6), 557-577(2006).
  5. T. Ouchi, T. Kontani, R. Aoki, T. Saito, Y. Ohya, Characteristic Properties of Film Prepared from Poly(L-lactide)-Grafted Dextran of Relatively High Sugar Unit Content as a Degradable Biomaterial, J. Polym. Sci. Part A Polym. Chem., 44(21), 6402-6409 (2006).

2005

  1. Y. Ohya, M. Toyohara, M. Sasakawa, H. Arimura, T. Ouchi, Thermosensitive Biodegradable Polydepsipeptide, Macromol. Biosci., 5(4), 273-276 (2005).
  2. H. Arimura, Y. Ohya, T. Ouchi, Formation of Core-Shell Type Biodegradable Polymeric Micelles from Amphiphilic Poly(Aspartic Acid)-block-Polylactide Diblock Copolymer, Biomacromolecules, 6(2), 720-725 (2005).
  3. Y. Ohya, A. Nakajima, T. Ouchi, Time-Resolved Laser Spectroscopic Analysis of Multi-Step Fluorescence Resonance Energy Transfer on Chromophore Array Constructed by Oligo-DNA Assembly, Supramol. Chem., 17(4), 283-289 (2005).
  4. T. Ouchi, T. Kontani, T. Saito, Y. Ohya, Suppression of Cell Attachment and Protein Adsorption onto Amphiphilic Polylactide-Grafted Dextran Films, J. Biomat. Sci. Polym. Ed., 16(8), 1035-1045 (2005).
  5. H. Arimura, T. Ouchi, A. Kishida, Y. Ohya, The Preparation of a Hyaluronic Acid Hydrogel through Polyion Complex Formation using Cationic Poly(Lactic Acid)-based Microspheres as a Biodegradable Crosslinking Agent, J. Biomat. Sci. Polym, 16(11), 1347-1358 (2005).

2004

  1. H. Arimura, Y. Ohya, T. Ouchi, H. Yamada, Preparation of a Biodegradable Matrix through Polyion Complex Formation by Mixing Polylactide-Based Microspheres Having Oppositely Charged Surfaces, J. Colloid Interface Sci., 270(2), 299-303 (2004).
  2. Y. Ohya, H. Matsunami, T. Ouchi, Cell Growth on the Porous Sponges Prepared from Poly(Depsipeptide-co-Lactide) Having Various Functional Groups, J. Biomat. Sci Polym. Edn., 15(1), 111-124 (2004).
  3. T. Ouchi, E. Yamabe, K. Hara, M. Hirai, Y. Ohya, Design of Attachment Type of Drug Delivery System by Complex Formation of Avidin with Biotinyl Drug Model and Biotinyl Saccharide, J. Contr. Rel., 94(2-3), 281-291 (2004).
  4. T. Ouchi, Y. Ohya, Design of Lactide Copolymers as Biomaterials, J. Polym. Sci. Part A Polym. Chem., 42(3), 453-462 (2004).
  5. T. Ouchi, M. Sasakawa, H. Arimura, Y. Ohya, Preparation of Poly[DL-Lactide-co-Glycolide]-Based Microsheres Containing Protein by Use of Amphiphilic Diblock Copolymers of Depsipeptide and Lactide Having Ionic Pendant Groups as Biodegradable Surfactant by W/O/W Emulsion Method, Polymer, 45(5), 1583-1589 (2004).
  6. Y. Ohya, H. Noro, T. Ouchi, Formation of Polymeric Assembly by Anti-Directed Oligo-DNA Dimers, Supramol. Chem., 16(3), 157-163 (2004).
  7. H. Arimura, Y. Ohya, T. Ouchi, The Formation of Biodegradable Polymeric Micelles from Newly Synthesized Poly(Aspartic Acid)-block-Polylactide AB-type Diblock Copolymer, Macromol. Rapid Commun., 25(6), 743-747 (2004).
  8. T. Ouchi, T. Saito, T. Kontani, Y. Ohya, Encapsulation and/or Release Behavior of Bovine Serum Albumin within and from Polylactide-Grafted Dextran Microspheres, Macromol. Biosci., 4(4), 458-463 (2004).
  9. T. Ouchi, T. Minari, Y. Ohya, Synthesis of Polylactide-Grafted Pullulan through a Coupling Reaction between Amino Group End-Capped Polylactide and Carboxymethyl Pullulan and Its Aggregation Behavior in Water. J. Polym. Sci. Part A Polym. Chem., 42, 5482-5487 (2004).
  10. T. Kimura, A. Okuno, K. Miyazaki, T. Furuzono, Y. Ohya, T. Ouchi, S. Mutsuo, H. Yoshizawa, Y. Kitamura, T. Fujisato, A. Kishida, Novel PVA-DNA Nanoparticles Prepared by Ultra High Pressure Technology for Gene Delivery. Material Science & Engineering C, 24(6-8), 797-801 (2004).

2003

  1. Y. Ohya, K. Yabuki, M. Tokuyama, T. Ouchi, Construction of Sequential Chromophore Arrays on Oligo-DNA Assembly and Their Energy Transfer Behavior, Supramol. Chem., 15(1), 45-54 (2003).
  2. H. Arimura, Y. Ohya, T. Ouchi, H. Yamada, Preparation of Polylactide Microspheres Having Positively or Negatively Charged Surfaces, Macromol. Biosci., 3(1), 18-25 (2003).
  3. Y. Ohya, H. Matsunami, E. Yamabe, T. Ouchi, Cell Attachment and Growth on Films Prepared from Poly(Depsipeptide-co-Lactide) Having Various Functional Groups, J. Biomed. Mater. Res., 65A(1), 79-88 (2003).
  4. Y. Ohya, K. Yabuki, T. Ouchi, Sequence Dependence of Fluorescent Quenching of Chromophores Covalently Bonded to Oligo-DNAs before and after Duplex Formation, Supramol. Chem. 15(2), 149-154 (2003).
  5. T. Ouchi, T. Uchida, H. Arimura, Y. Ohya, Synthesis Poly(L-Lactide) End-Capped with Lactose Residue, Biomacromolecules, 4(3), 477-480 (2003).
  6. T. Ouchi, T. Kontani, Y. Ohya, Modification of Polylactide upon Physical Properties by Solution-Cast Blends from Polylactide and Polylactide-grafted Dextran, Polymer, 44(14), 3927-3932 (2003).
  7. T. Ouchi, T. Kontani, Y. Ohya, Mechanical Properties and Biodegradability of Solution-Cast Film Prepared from Amphiphilic Polylactide-Grafted Dextran, J. Polym. Sci. Part A Polym. Chem., 41(16), 2462-2468 (2003).
  8. Y. Ohya, K. Yabuki, M. Hashimoto, A. Nakajima, T. Ouchi, Multi-Step Fluorescence Resonance Energy Transfer in Sequential Chromophore Array Constructed on Oligo-DNA Assemblies, Bioconjugate Chem., 14(6), 1057-1066 (2003).
  9. H. S. Choi, T. Ooya, S. Sasaki, N. Yui, Y. Ohya, T. Nakai, T. Ouchi, Preparation and Characterization of Polypseudorotaxanes Based on Biodegradable Poly(L-Lactide)/Poly(Ethylene Glycol) Triblock Copolymers, Macromolecules, 36(25), 9313-9318 (2003).

2002

  1. T. Ouchi, M. Toyohara, H. Arimura, Y. Ohya, Preparation of Poly(L-Lactide)-Based Microspheres Having Cationic or Anionic Surface Using Biodegradable Surfactants, Biomacromolecules, 3(5), 885-888 (2002).
  2. T. Ouchi, H. Miyazaki, H. Arimura, F. Tasaka, A. Hamada, Y. Ohya, Synthesis of Biodegradable Amphiphilic AB-Type Diblock Copolymers of Lactide and Depsipeptide with Pendant Reactive Groups, J. Polym. Sci. Part A Polym. Chem., 40(9), 1218-1225 (2002).
  3. T. Ouchi, H. Miyazaki, H. Arimura, F. Tasaka, A. Hamada, Y. Ohya, Formation of Polymeric Micelle Having Amino Surface from Amphiphilic AB-Type Diblock Copolymers Composed of Poly(Glycolic Acid-Lysine) Segment and Polylactide Segment, J. Polym. Sci. Part A Polym. Chem., 40(10), 1426-1432 (2002).

2001

  1. F. Tasaka, Y. Ohya, T. Ouchi, Synthesis of Novel Comb-Type Polylactide and Its Biodegradability, Macromolecules, 34(16), 5494-5500 (2001).
  2. F. Tasaka, Y. Ohya, T. Ouchi, One-Pot Synthesis of Novel Branched Polylactide through Copolymerization of Lactide with Mevalonolactone, Macromol. Rapid Commun., 22(11), 820-824 (2001).
  3. Y. Ohya, H. Oue, K. Nagatomi, T. Ouchi, Design of Macromolecular Prodrug of Cisplatin Using Dextran with Branched Galactose Units as Targeting Moieties to Hepatoma Cells, Biomacromolecules, 2(3), 927-933 (2001).
  4. Y. Ohya, K. Nagatomi, T. Ouchi, Synthesis and Cytotoxic Activity of Macromolecular Prodrug of Cisplatin Using Poly(Ethylene Glycol) Having Galactose Residue or Antennary Galactose Unit, Macromol. Biosci., 1(8), 355-363 (2001).
  5. T. Ouchi, T. Uchida, Y. Ohya, Synthesis of Poly(L-Lactic Acid) Having One Terminal D-Glucose Residue and Wettability of Its Film Surface, Macromol. Biosci., 1(9), 371-375 (2001).

2000

  1. Y. Ohya, R. Cai, H. Nishizawa, K. Hara, T. Ouchi, Preparation of PEG-Grafted Chitosan Nanoparticles as Peptide Drug Carriers, STP Pharma Sci., 10(1), 77-82 (2000).
  2. K. Ichinose, N. Tomiyama, M. Nakashima, Y. Ohya, M. Ichikawa, T. Ouchi, T. Kanematsu, Antitumor Activity and Toxicity of Dextran Derivatives Immobilizing Platinum Complex(II), Anticancer Drugs, 11(1), 33-38 (2000).
  3. T. Ouchi, H. Seike, H. Miyazaki, F. Tasaka, Y. Ohya, Synthesis of Block Copolymer of L-Lactide and Depsipeptide with Pendant Thiol Groups, Desinged Monom. Polym. 3(3), 279-287 (2000).
  4. Y. Ohya, S. Shirakawa, M. Matsumoto, T. Ouchi, Design of Poly(Ethylene Glycol) Immobilizing Platinum Complex through Chelate-Type Coordination Bond, Polym. Adv. Technol., 11(8-12), 635-641 (2000).
  5. Y. Ohya, K. Yabuki, M. Komatsu, T. Ouchi, Sequential Arrangement of Chromophores and Energy Transfer Behavior on Oligonucleotides Assemblies, Polym. Adv. Technol., 11(8-12), 845-855 (2000).

1999

  1. T. Ouchi, A. Hamada, Y. Ohya, Biodegradable Microspheres Having Reactive Groups Prepared from L-Lactic Acid-Depsipeptide Copolymers, Macromol. Chem. Phys., 200, 436-441 (1999).
  2. Y. Ohya, S. Maruhashi, K. Shizuno, S. Mano, J. Murata, T. Ouchi, Graft Polymerization of Styrene on Chitosan and the Characteristics of the Copolymers, J. Macromol. Sci.-Pure Appl. Chem., A36(3), 339-353 (1999).
  3. M. Nakashima, K. Ichinose, T. Kanematsu, T. Masunaga, Y. Ohya, T. Ouchi, N. Tomiyama, H. Sasaki, M. Ichikawa, In Vitro Characteristics and in Vivo Plasma Disposition of Cisplatin Conjugated with Oxidized and Dicarboxymethylated Dextrans, Biol. Pham. Bull., 22(7), 765-761 (1999).
  4. F. Tasaka, H. Miyazaki, Y. Ohya, T. Ouchi, Synthesis of Comb-Type of Biodegradable Polylactide through Depsipeptide-Lactide Copolymer Containing Serine Residues, Macromolecules, 32(19), 6386-6389 (1999).
  5. T. Ouchi, J. Murata, Y. Ohya, Gene Delivery by Quaternary Chitosan with Antennary Galactose Residues, ACS Symp. Ser., 737, 15-23 (1999).

1998

  1. T. Ouchi, H. Seike, T. Nozaki, Y. Ohya, Synthesis and Characteristics of Polydepsipeptide with Pendant Thiol Groups, J. Polym. Sci. Part A Polym. Chem., 36, 1283-1290 (1998).
  2. Y. Ohya, Y. Okuyama, A. Fukunaga, T. Ouchi, Photo-Sensitive Lipid Membrane Perturbation by Single Chain Lipid Having Terminal Spiropyran Group, Supramol. Sci., 5, 21-29 (1998).
  3. K. Ichinose, K. Nakata, N. Ishii, Y. Ohya, T. Ouchi, T. Kanematsu, Cell-Type-Specific Augmentation of the Tumoricidal Activity of Polymeric Adriamycin Combined with Galactose, Acta Med. Nagasaki., 43, 12-15 (1998).
  4. Y. Ohya, S. Maruhashi, T. Ouchi, Graft Polymerization of L-Lactide on Pullulan through Trimethylsilyl Protection Method and Degradation of the Graft Copolymers, Macromolecules, 31(14), 4662-4665 (1998).
  5. T. Ouchi, M. Tada, M. Matsumoto, Y. Ohya, K. Hasegawa, Y. Arai, K. Kadowaki, S. Akao, T. Matsumoto, S. Suzuki, M. Suzuki, Design of Macromolecular Prodrug of 5-Fluorouracil Using N-Acetylpolygalactosamine as a Targeting Carrier to Hepatoma, React. Funct. Polym., 37, 235-244 (1998).
  6. T. Ouchi, H. Nishizawa, Y. Ohya, Aggregation Phenomenon of PEG-Grafted Chitosan in Aqueous Solution, Polymer, 39(21), 5171-5175 (1998).
  7. T. Ouchi, M. Tada, M. Matsumoto, Y. Ohya, K. Hasegawa, Y. Arai, K. Kadowaki, S. Akao, T. Matsumoto, S. Suzuki, M. Suzuki, Design of Lysosomotropic Macromolecular Prodrug of Doxorubicin Using N-Acetyl-α-1,4-Polygalactosamine as a Targeting Carrier to Hepatoma Tissue, J. Bioact. Compat. Polym., 13(4), 257-269 (1998).
  8. Y. Ohya, S. Maruhashi, T. Ouchi, Preparation of Poly(Lactic Acid)-Grafted Amylose through Trimethylsilyl Protection Method and Its Biodegradation, Macromol. Chem. Phys., 199, 2017-2022 (1998).
  9. Y. Ohya, T. Masunaga, T. Ouchi, K. Ichinose, M. Nakashima, M. Ichikawa, T. Kanematsu, Antitumor Drug Delivery by Dextran Derivatives Immobilizing Platinum Complex (II) through Coordination Bond, ACS Symp. Ser., 709, 266-278 (1998).

1997

  1. J. Murata, T. Kitamoto, Y. Ohya, T. Ouchi, Effect of Dimerization of the D-Glucose Analogue of Muramyl Dipeptide on Stimulation of Macrophage-like Cells, Carbohydr. Res., 297, 127-133 (1997).
  2. J. Murata, Y. Ohya, T. Ouchi, Design of Quaternary Chitosan Conjugate Having Antennary Galactose Residues as a Gene Delivery Tool, Carbohydr. Polym., 32, 105-109 (1997).
  3. T. Ouchi, T. Nozaki, A. Ishikawa, I. Fujimoto, Y. Ohya, Synthesis and Enzymatic Hydrolysis of Lactic Acid-Depsipeptide Copolymers with Functionalized Pendant Groups, J. Polym. Sci. Part A Polym. Chem., 35(2), 377-383 (1997).
  4. T. Ouchi, M. Matsumoto, K. Ihara, Y. Ohya, Synthesis and Cytotoxic Activity of Oxidized Galactomannan/ADR Conjugate, J. Macromol. Sci.-Pure Appl. Chem., A34(6), 975-989 (1997).
  5. D. Magda, S. Crofts, J. L. Sessler, P. Sansom, S. L. Springs, Y. Ohya, Energy Transfer Assemblies Composed of Expanded Porphyrin-Oligonucleotide Conjugates, Tetrahedron Lett., 38(33), 5759-5762 (1997).
  6. J. Murata, H. Nagae, Y. Ohya, T. Ouchi, Design of Macromolecular Biological Response Modifier by Immobilizing of D-Glucose Analogue of Muramyl Dipeptide on Carboxymethyl-Dextran Having Mannose Branches, J. Biomat. Sci. Polym. Edn., 8(12), 931-946 (1997).
  7. T. Ouchi, H. Kuroda, Y. Ohya, Design of Antitumor Agent-Terminated Poly(Ehtylene Glycol) Conjugate as Macromolecular Prodrug, ACS Symp. Ser., 680, 284-296 (1997).

1996

  1. Y. Ohya, T. Masunaga, T. Baba, T. Ouchi, Synthesis and Cytotoxic Activity of Dextran Immobilizing Platinum(II) Complex through Chelate-Type Coordination Bond, J. Macromol. Sci.-Pure Appl. Chem., A33(8), 1005-1016 (1996).
  2. J. Murata, Y. Ohya, T. Ouchi, Possibility of Application of Quaternary Chitosan Having Pendant Galactose Residues as Gene Delivery Tool, Carbohydr. Polym., 29(1), 69-74 (1996).
  3. Y. Ohya, H. Noro, M. Komatsu, T. Ouchi, Synthesis of Symmetric Oligo-DNA Dimers and Their Formation of Polymeric Supramolecular Assembly, Chem. Lett., 25, 447-448 (1996).
  4. Y. Ohya, T. Masunaga, T. Baba, T. Ouchi, Synthesis and Cytotoxic Activity of Dextran Carrying cis-Dichloro(cyclohexane-trans-l-1,2-diamine)platinum(II) Complex, J. Biomat. Sci. Polym. Edn., 7(12), 1085-1096 (1996).
  5. Y. Ohya, K. Okawa, J. Murata, T. Ouchi, Preparation of Oxidized 6-O-Glycolchitosan, pH Sensitivity of Its Aqueous Solution and of Its Cross-Linked Hydrogel, Angew. Makromol. Chem., 240, 263-273 (1996).
  6. T. Ouchi, T. Nozaki, Y. Okamoto, M. Shiratani, Y. Ohya, Synthesis and Enzymatic Hydrolysis of Polydepsipeptides with Functionalized Pendant Groups, Macromol. Chem. Phys., 197, 1823-1833 (1996).
  7. J. Murata, H. Nagae, Y. Ohya, T. Ouchi, Synthesis of Muramyl Dipeptide Analogue/Glucomannan Conjugate and Its Stimulation Activity against Macrophage-Like Cells Carbohydr. Polym., 29, 111-118 (1996).
  8. Y. Ohya, J. Miyaoka, T. Ouchi, Recruitment of Enzyme Activity in Albumin by Molecular Imprinting, Macromol. Rapid Commun., 17, 871-874 (1996).

1995

  1. Y. Ohya, T. Sugitou, T. Ouchi, Polycondensation of α-Hydroxy Acids by Enzymes or PEG-Modified Enzymes in Organic Media, J. Macromol. Sci.-Pure Appl. Chem., A32(2), 179-190 (1995).
  2. Y. Ohya, H. Kuroda, K. Hirai, T. Ouchi, Synthesis and Cytotoxic Activity of Conjugates of Monomethoxy-Poly(Ethylene Glycol) End-Capped with Doxorubicin via Ester, Amide or Schiff’s Base Bond, J. Bioact. Compat. Polym., 10(1), 51-66 (1995).
  3. Y. Ohya, K. Nonomura, T. Ouchi, In Vivo and In Vitro Antitumor Activity of CM-Chitin Immobilizing Doxorubicins through Lysosomally Digestible Tetrapeptide Spacer Groups, J. Bioact. Compat. Polym., 10(3), 223-234 (1995).

1994

  1. Y. Ohya, T. Nishimoto, J. Murata, T. Ouchi, Immunological Enhancement Activity of Muramyl Dipeptide Analogue/CM-Curdlan Conjugate, Carbohydr. Polym., 23, 47-54 (1994).
  2. T. Ouchi, K. Inosaka, Y. Ohya, Use of α-1,4-Polygalactosamine as a Carrier of Macromolecular Prodrug of 5-Fluorouracil, ACS Symp. Ser., 545, 204-213 (1994).
  3. Y. Ohya, M. Shiratani, H. Kobayashi, T. Ouchi, Release Behavior of 5-Fluorouracil from Chitosan-Gel Microspheres Immobilizing 5-Fluorouracil Coated with Polysaccharides and Their Cell Specific Cytotoxicity, J. Macromol. Sci.-Pure Appl. Chem., A31, 629-642 (1994).
  4. Y. Ohya, K. Nonomura, K. Hirai, T. Ouchi, Synthesis of CM-Chitin Immobilizing Doxorubicins through Tetrapeptide Spacer Groups and Its Enzymatic Release Behavior of Doxorubicin in Vitro, Macromol. Chem. Phys., 195, 2839-2853 (1994).
  5. T. Ouchi, H. Kuroda, K. Hirai, Y. Ohya, Design of Drug-Terminated Poly(Ethylene Glycol) Conjugate Exhibiting Antitumor Activity, J. Macromol. Sci.-Pure Appl. Chem., A31(Suppls. 6&7), 1091-1099 (1994).
  6. Y. Ohya, K. Ihara, J. Murata, T. Sugitou, T. Ouchi, Preparation and Biological Properties of Dicarboxy-Glucomannan: Enzymatic Degradation and Stimulating Activity against Cultured Macrophages, Carbohydr. Polym., 25(2), 123-130 (1994).

1993

  1. Y. Ohya, T. Nishimoto, T. Ouchi, Design of D-Glucose Analogue of MDP/CM-Curdlan Conjugate and Its Immunological Enhancement Activity, Carbohydr. Polym., 20, 43-49 (1993).
  2. Y. Ohya, T. Takei, T. Ouchi, Release Behavior of 5-Fluorouracil from Chitosan-Gel Microspheres Immobilizing 5-Fluorouracil Derivative Coated with Polysaccharides and Their Cell Specific Recognition, J. Microencap., 10, 1-9 (1993).
  3. T. Ouchi, H. Kobayashi, K. Hirai, Y. Ohya, Design of Poly(α-Malic Acid)-Antitumor Drug-Saccharide Conjugate Exhibiting Cell-Specific Antitumor Activity, ACS Symp. Ser., 520, 382-394 (1993).
  4. Y. Ohya, J. Murata, T. Nishimoto, T. Ouchi, Synthesis of a MDP Analogue/Chitin Conjugate That Stimulates Cultured Macrophages, J. Bioact. Compat. Polym., 8, 351-364 (1993).
  5. T. Ouchi, M. Shiratani, M. Jinno, M. Hirao, Y. Ohya, Synthesis of Poly[(Glycolic Acid)-alt-(L-Aspartic Acid)] and Its Biodegradation Behavior in Vitro, Makromol. Chem. Rapid Commun., 14, 825-831 (1993).

1992

  1. Y. Ohya, K. Inosaka, T. Ouchi, Synthesis and Antitumor Activity of 6-O-Carboxymethyl Chitin Fixing 5-Fluorouracils through Pentamethylene, Monomethylene Spacer Groups via Amide, Ester Bonds, Chem. Pharm. Bull., 40, 559-561 (1992).
  2. Y. Ohya, T. Nakao, T. Ouchi, T. Inoi, K. Fukushima, T. Tashiro, Antitumor Activity of Vinyl Polymer Immobilized 5-Fluorouracils through Organosilicon-Amine Spacer Groups via Urea Bonds, J. Macromol. Sci.-Pure Appl. Chem., A29, 503-515 (1992).
  3. Y. Ohya, T. Takei, T. Ouchi, Thermo-Sensitive Release Behavior of 5-Fluorouracil from Chitosan-Gel Microspheres Coated with Lipid Multilayers, J. Bioact. Compat. Polym., 7, 242-256 (1992).
  4. Y. Ohya, K. Hirai, T. Ouchi, Synthesis and Cytotoxic Activity of Doxorubicin Bound to Poly(α-Malic Acid) via Ester or Amide Bonds, Makromol. Chem., 193, 1881-1887 (1992).

1991

  1. T. Ouchi, T. Banba, T. Z. Huang, Y. Ohya, Design of Polysaccharide-5-Fluorouracil Conjugates Exhibiting Antitumor Activity, ACS Symp. Ser., 469, 71-83 (1991).
  2. Y. Ohya, T. Takei, H. Fukushima, T. Ouchi, Preparation of Albumin Microspheres Grafted Galactose Residues through Polyethylene-Glycol Spacers, Release Behavior of 5-Fluorouracil from Them, and Their Lectin-Mediated Aggregation, J. Macromol. Sci.-Chem., A28, 743-760 (1991).
  3. Y. Ohya, H. Kobayashi, T. Ouchi, Design of Poly(α-Malic Acid)-5FU-Saccharide Conjugate Exhibiting Antitumor Activity, React. Polym., 15, 153-163 (1991).
  4. Y. Ohya, T. Z. Huang, T. Ouchi, K. Hasegawa, J. Tamura, K. Kadowaki, T. Matsumoto, S. Suzuki, M. Suzuki, Synthesis and Antitumor Activity of α-1,4-Polygalactosamine and N-Acetyl-α-1,4-Polygalactosamine Immobilized 5-Fluorouracils through Hexamethylene Spacer Groups via Urea, Urea Bonds, J. Contr. Rel., 17, 259-266 (1991).

著書・総説  ―Books and reviews―

2020

  1. 大矢裕一, 生体内で分解される高分子:DDSと再生医療への応用,現代化学, 60-63 (2020.4).
  2. 大矢裕一, 医用高分子(総論), 高分子材料の辞典,高分子学会編,朝倉書店, 印刷中.
  3. 大矢裕一,「関大メディカルポリマー」の開発と医療応用, 機能材料,3-13 (2020).

2019

  1. Y. Ohya, Temperature-responsive Biodegradable Injectable Polymer Systems with Conveniently Controllable Properties, Polym. J., 51(10), 997-1005, (2019.10) DOI : 10.1038/s41428-019-0217-0
  2. 大矢裕一, 温度応答性ポリマーを利用した生体適合性材料の開発,「無機/有機材料の表面処理・改質による生体適合性付与」, 蓜島由二監修,シーエムシー出版, 218-227.(2019.5)総ページ数315.

2018

  1. 大矢裕一, 生体内でゲル状態を制御できるインジェクタブルポリマーの開発,「ゲル化・増粘剤の使い方、選び方 事例集」,技術情報協会,p542-549, 総ページ数691(2018.2.28).
  2. 山岡哲二,大矢裕一,中野貴由, 石原一彦,バイオマテリアルサイエンス第二版 -基礎から臨床まで-,東京化学同人, 総ページ数224 (2018.4). 

2017

  1. 大矢裕一, 生分解性高分子の医療応用, 「CSJカレントレビュー24『化学で医療・診断・創薬の革新を目指す』」, 化学同人, 98-105 (2017).
  2. 大矢裕一, 温度応答性インジェクタブルポリマー,「医療用バイオマテリアルの研究開発」, 青柳隆夫監修,シーエムシー出版, 107-116 (2017.2).総ページ数258.
  3. 大矢裕一, DDS用高分子の最新開発状況,「DDS先端技術の製剤への応用開発」,技術情報協会,371-379 (2017.6).総ページ数492.
  4. 大矢裕一, 内視鏡下で使用できる癒着防止材を目指した温度応答性インジェクタブルポリマーの開発,マテリアルステージ, 17(3), 34-39 (2017.6).
  5. 大矢裕一,生分解性高分子のスマートな医療応用~Mixing strategyによるインジェクタブルポリマーの機能向上,工業材料, 65(7), 50-55 (2017.6).
  6. 大矢裕一, ポリ乳酸系高分子を用いた分解吸収速度の調節を目的とした分子設計,「生体吸収性材料の開発とその安全性評価」,技術情報協会,189-196(2017.12)

2016

  1. 大矢裕一, 平野義明,高分子材料,「バイオマテリアル その基礎と先端研究への展開」,岡野光夫監修,田端泰彦,塙隆夫編,東京化学同人,27-51 (2016.2).
  2. 大矢裕一, 高機性能生分解性インジェクタブルポリマーの開発, 高分子, 65(11), 636-640(2016).
  3. Y. Ohya, Injectable Hydrogels, Biomaterials Nanoarchitectonics: Design of Functional Nanomaterials for Biomedical Applications, Ed. M. Ebara, Elsevier, 41-57 (2016).

2015

  1. 大矢裕一, DDSに使われる材料, J. Antibact. Antifung. Agents, 43(1),41-48 (2015.1).
  2. 大矢裕一, 総論 医療用バイオベースマテリアル,「進化する医療用バイオベースマテリアル」, 大矢裕一, 相羽誠一監修, シーエムシー出版, 1-12 (2015.1).
  3. 大矢裕一, 生分解性スマートバイオマテリアル,「進化する医療用バイオベースマテリアル」, 大矢裕一, 相羽誠一監修, シーエムシー出版, 235-243 (2015.1).
  4. Y. Ohya, Biodegradable Materials, Encyclopedia of Polymeric Nanomaterials, Eds. S. Kobayashi and K. Mullen, Springer, 139-145 (2015). 10.1007/978-3-642-29648-2.

2014

  1. 大矢裕一, 生体内分解性,化学便覧応用化学編,日本化学会編,丸善, 1509-1510 (2014.1).
  2. 大矢裕一, 体温でゲル化する生分解性高分子,「ゲルテクノロジーハンドブック」,エヌティーエス,764-768 (2014.10). 総ページ数835.
  3. 大矢裕一, 生分解・吸収性が必要な高分子バイオマテリアル,「生体適合性制御と要求特性掌握から実践する高分子バイオマテリアルの設計・開発戦略~モノマー(いち)からデザインするバイオインターフェースと上市までの道筋~」,サイエンス&テクノロジー, 51-73 (2014.5).総ページ数426
  4. 大矢裕一, 横山昌幸,ドラッグデリバリーシステム(DDS)の基礎,J. Antibact. Antifung. Agents, 42(12), 697-700 (2014.12).
  5. K. Kuzuya, Y. Ohya, Nanomechanical molecular devices made of DNA origami, Acc. Chem. Res., 47(6), 1742-1749 (2014).

2013

  1. 大矢裕一, 合成高分子(吸収性),遺伝子医学Mook別冊「ここまで広がるドラッグ徐放技術の最前線」,田端泰彦編,メディカルドゥ, 34-39 (2013.3).
  2. 大矢裕一, 医療用途を目指した温度応答型スマートポリマーの設計,機能材料, 33(8), 42-49 (2013).
  3. 大矢裕一, ポリ乳酸の活用と研究開発テーマの発掘,「技術シーズを活用した研究開発テーマの発掘」,技術情報協会,667-676(2013.7).
  4. 大矢裕一, 鋭敏な温度応答性を示す生分解性形状記憶ポリマー,「体内埋め込み医療材料の開発とその理想的な性能・デザインの要件」,技術情報協会,382-386 (2013.10).
  5. K. Nagahama, A. Takahashi, Y. Ohya, Biodegradable polymers exhibiting temperature-responsive sol-gel transition as injectable biomedical materials, React. Funct. Polym., 73, 979-985 (2013).
  6. Y. Ohya, Polymeric micelles stabilized by electrostatic interactions for drug delivery, ACS Symp. Ser., 1135, 87-101 (2013).

2012

  1. 大矢裕一, 生分解性インジェクタブルポリマー, 「医療を支える先端バイオマテリアル」, 秋吉一成,石原一彦,山岡哲二監修, エヌティーエス, 336-341 (2012).
  2. Y. Ohya, A. Takahashi, K. Nagahama, Biodegradable Polymeric Assemblies for Biomedical Materials, Adv. Polym. Sci., 247, 65-114 (2012).
  3. A. Kuzuya, Y. Ohya, DNA nanostructures as scaffolds for metal nanoparticles, Polym. J., 44, 452-460 (2012).

2011

  1. 大矢裕一, ドラッグデリバリーを指向した生分解性ナノ粒子の調製, 化学工業, 62(7) 571-578 (2011).
  2. 大矢裕一, 生体吸収性および非吸収性高分子,「ものづくりからみる再生医療-細胞研究・創薬・治療」, 田畑泰彦監修,シーエムシー出版, 67-77 (2011).

2010

  1. 大矢裕一, 生分解性ゲル,「食品・医薬品・医療分野へのゲルの利用」, シーエムシー出版, 193-199 (2010).
  2. 大矢裕一, 多糖-生分解性合成高分子ハイブリッドの医療応用, 高分子, 59(6), 418-419 (2010).
  3. 大矢裕一, 両親媒性生分解性ポリマーを用いたDDS用微粒子の調製, Pharm Tech Japan, 26(10), 1979-1989 (2010).
  4. 大矢裕一, 「バイオマテリアルの基礎」, 日本医学館,110-118(2010).

2009

  1. 大矢裕一, 合成高分子(生体吸収性), 遺伝子医学Mook別冊「ますます重要になる細胞周辺環境(細胞ニッチ)の最新科学技術」,田端泰彦編,メディカルドゥ,43-49 (2009).
  2. DNAナノアレイと開閉可能なDNAナノボックス-DNAはナノマテリアルとして実用可能か?,化学,64(8), 72-73 (2009).
  3. Y. Ohya, Construction of Molecular Arrangement by DNA Assembly, Bottom-up Nanofablication, Eds. K. Ariga and H. S. Nalwa, American Scientific Publishers, Valencia CA USA, 323-335 (2009).

2008

  1. 長濱宏治,大矢裕一, ポリ乳酸系ゲルのバイオマテリアルへの応用,「医療用ゲルの最新技術と開発」, シーエムシー出版, 201-205 (2008).
  2. 大矢裕一, 長濱宏治, 生分解性高分子材料, Drug Delivery System, 23(6), 618-626 (2008).

2007

  1. 大矢裕一, ポリマーバイオマテリアルの作り方, バイオマテリアル, 25(1), 18-26 (2007).
  2. 大矢裕一, ポリ乳酸系ポリマーのDDSへの応用, バイオインダストリー, 24(3), 16-27 (2007).
  3. 大矢裕一, 合成ポリペプチド,ポリデプシペプチド, 遺伝子医学Mook別冊「絵で見て分かるナノDDS」,田端泰彦編,メディカルドゥ, 34-44 (2007).

2006

  1. 大矢裕一, DNAを用いた分子組織体の構築, 高分子, 55(1), 31-36 (2006).
  2. 大内辰郎, 大矢裕一,ポリ乳酸系ソフト医用材料の創製, ケミカルエンジニアリング, 51(1), 19-22 (2006).

2005

  1. 大矢裕一, 生分解性材料、”医療用マテリアルと機能膜”, 樋口亜紺監修, シーエムシー出版, 13-25 (2005).
  2. 大矢裕一, 高分子辞典 第3版, 高分子学会編集, 朝倉書店(2005).

2004

  1. 大矢裕一, DNA分子組織体上でのクロモフォアの配列化, オレオサイエンス, 4(1), 5-10 (2004).
  2. 大矢裕一, 多様な物性を示す新規なポリ乳酸系生分解性高分子の合成とバイオマテリアルとしての応用 , バイオマテリアル, 22(1), 24-35 (2004).
  3. 大矢裕一, DNAの組織化による分子配列制御、”ナノバイオエンジニアリングマテリアル”, 石原一彦監修, フロンティア出版, 177-186 (2004).
  4. 大内辰郎, 大矢裕一, 新規なポリ乳酸系医用材料, 関西大学工業技術研究所報 技苑, 117, 7-12 (2004).

2003

  1. 石原一彦,畑中研一,山岡哲二,大矢裕一,バイオマテリアルサイエンス,東京化学同人 (2003).
  2. Y. Ohya, Design of Novel Biodegradable Lactic Acid Copolymers for Biomaterials, In “Advances in Biomaterials and Drug Delivery Systems”, Eds. G. H. Hsiue, T. Okano, U. Y. Kim, H. W. Sung, N. Yui, K. D. Park, Princeton International Publishing Co., Ltd., Taipei, 263-278 (2003).
  3. Y. Ohya, New Class of Lactic Acid Copolymers with Reactive and Hydrophilic Segments for Degradable Biomedical Materials, Materials Science Forum, 426-432, Eds. T. Chandra, J. M. Torralba, T. Sakai, Trans Tech Publications, Switzerland, 3231-3236 (2003).
  4. Y. Ohya, N. Ohe, T. Ouchi, W. J. Kim, T. Akaike, A. Maruyama, Energy Transfer Behavior in Chromophore Array Constructed by DNA Assembly in the Presence of Polycationic Graft Copolymer, Biomolecular Chemistry – A Bridge for the Future, Edited by Scientific Program Committee of ISBC2003, Maruzen Co., Ltd., 332-333 (2003).

2002

  1. 大内辰郎, 大矢裕一, 新規なポリ乳酸系医用材料, 未来材料, 2(3), 30-35 (2002).
  2. 大矢裕一, ポリ乳酸をベースとした新規な生分解性高分子の合成とバイオマテリアルとしての応用, 高分子論文集, 59(8), 484-498 (2002).
  3. N. Yui, A. Kishida, T. Yamaoka, Y. Ohya, General Introduction, In “Supramolecular Design for Biological Applications”, Ed. N. Yui, CRC Press, Boca Raton, USA, 1-9 (2002).
  4. Y. Ohya, Hydrogen Bonds, In “Supramolecular Design for Biological Applications”, Ed. N. Yui, CRC Press, Boca Raton, 25-64 (2002).

2001

  1. 大矢裕一, 大内辰郎, DNAを用いた分子素子, 関西大学工業技術研究所報 技苑, 107, 3-8 (2001).
  2. 大内辰郎, 大矢裕一, 制がん剤シスプラチンの高分子プロドラッグ化, ファルマシア, 37(5), 393-395 (2001).
  3. 大矢裕一, 大内辰郎, 高分子キャリア, Drug Delivery System, 16(3), 143-153 (2001).
  4. 大内辰郎, 大矢裕一, 生分解性バイオマテリアルの設計および医療用材料への応用, 関西大学工業技術研究所報 技苑, 108, 34-35 (2001).
  5. Y. Ohya, S. Maruhashi, T. Hirano, T. Ouchi, Preparation of Poly(Lactic Acid)-Grafted Polysaccharides as Biodegradable Amphiphilic Materials, In “Biomedical Polymers and Polymer Therapeutics”, Eds. E. Chiellini, J. Sunamoto, C. Migliaresi, R. M. Ottenbrite, D. Cohn, Kluwer Academic/Plenum Publishers, New York, 139-148 (2001).
  6. T. Ouchi, K. Nonomura, J. Murata, H. Nishizawa, Y. Ohya, Possibility of Application of Chitin and Chitosan as Drug Delivery Tools, In “Chitin and Chitosan, Chitin and Chitosan in Life Science”, Eds. T. Uragami, K. Kurita, T. Fukamizo, Kodansha Scientific Ltd., Tokyo, 178-185 (2001).
  7. Y. Ohya R. Cai, H. Nishizawa, K. Hara, T. Ouchi, Preparation of PEG-Grafted Chitosan Aggregates as Peptide Drug Carriers, In “Chitin and Chitosan, Chitin and Chitosan in Life Science”, Eds. T. Uragami, K. Kurita, T. Fukamizo, Kodansha Scientific Ltd., Tokyo, 210-213 (2001).

2000

  1. 大矢裕一, 人工材料(有機)-この1年の進歩, 人工臓器、29(5) , 619-620 (2000).
  2. 青田浩幸, 大矢裕一, 太陽光エネルギー変換有機デバイスの構築, 関西大学工業技術研究所報 技苑, 104, 24-25 (2000).

1999

  1. 大矢裕一, 生分解性高分子の現況と新展開, 人工臓器, 28(3), 582-589 (1999).
  2. 大矢裕一, 大内辰郎, 生分解性バイオマテリアルとしての新しいポリ乳酸系高分子, 高分子加工、48(12), 530-534 (1999).
  3. T. Ouchi, H. Nishizawa, Y. Ohya, Aggregation Phenomenon of PEG Grafted Chitosan in Aqueous Solution, In “Advances in Science and Technology. 13 Intelligent Materials and Systems”, Ed. P. Vincenzini, Techna Faenza, 169-176 (1999).
  4. T. Ouchi, H. Seike, A. Hamada, Y. Ohya, Biodegradable Polydepsipeptide with Functionalized Side-Chain groups as a Drug Carrier, In “Advances in Science and Technology. 13 Intelligent Materials and Systems”, Ed. P. Vincenzini, Techna Faenza, 177-184 (1999).

1998

  1. T. Ouchi, J. Murata, Y. Ohya, Possibility of Application of Quaternary Chitosan Conjugate Having Pendant Galactose Residues As Gene Delivery Tool, In “Advances in Chitin Science II”, Eds. A. Domard, G. A. F. Roberts, K. M. Varum, Jacques Andre Publisher, 870-877 (1998).

1997

  1. T. Ouchi, Y. Ohya, Synthetic Design by Modification of Natural Materials, In “Macromolecular Design of Polymeric Materials”, Eds. K. Hatada, T. Kitayama, O. Vogl, Marcel Dekker Inc., New York, 351-364 (1997).
  2. Y. Ohya, J. Murata, T. Ouchi, Cellular Gene Delivery Using Quaternary Chitosan Conjugate Having Antennary Galactose Residues, In “Advances in Polymeric Biomaterials Science”, Eds. T. Akaike, T. Okano, M. Akashi, M. Terano, N. Yui, CMC Co. Ltd., Tokyo, Japan, 575-584 (1997).

1996

  1. 大矢裕一, 大内辰郎, 生分解性ポリエステル:ポリリンゴ酸の開発, 関西大学工業技術研究所報 技苑, 89, 39-42 (1996).
  2. Y. Ohya, Y. Okuyama, T. Ouchi, Photo-Induced Drug Release from Liposome Using Photochromic Lipid Having Spiropyran Group, In “Advances in Biomedical Polymers in Biomedical Engineering and Drug Delivery Systems”, Eds. N. Ogata, S. W. Kim, J. Feijen, T. Okano, Springer-Verlag, 353-354 (1996).
  3. Y. Ohya, T. Kitamoto, J. Murata, T. Nishimoto H. Nagae, T. Ouchi, The Effect of Multivalent Ligand Formation on the Immunological Enhancement Activity of Muramyl Dipeptide(MDP) Analogue/Polymer Conjugates, In “Biomedical Functions and Biotechnology of Natural and Artificial Polymers”, Eds. M. Yalpani, ATL Press, Shrewbury, MA, USA, 127-134 (1996).
  4. Y. Ohya, Y. Iwao, T. Ouchi, Cell Growth by Multivalent Complex of Biotinyl Insulin and Avidin, In “Biomedical Materials Research in the Far East (II)”, Eds. Y. Ikada, X. Zhang, Kobunshi Kankokai, Tokyo, 73-74 (1996).
  5. J. Murata, Y. Ohya, T. Ouchi, Quaternary Chitosan/Galactose Conjugate as a Cell-Specific Gene Delivery Tool, In “Biomedical Materials Research in the Far East (II)”, Eds. Y. Ikada, X. Zhang, Kobunshi Kankokai, Tokyo, 155-156 (1996).

1995

  1. T. Ouchi, Y. Ohya, Macromolecular Prodrug, Prog. Polym. Sci., 20, 211-257 (1995).
  2. Y. Ohya, K. Ihara, J. Murata, T. Ouchi, Biodegradation and Immunological Enhancement Activity of Dicarboxy-Glucomannan Having Recognizable Branched Saccharide Residues, In “Advances in Science and Technology. 10 Intelligent Materials and Systems”, Ed. P. Vincenzini, Techna Faenza, 273-280 (1995).
  3. T. Ouchi, Y. Ohya, Synthesis of CM-Chitin/Doxorubicin Conjugate Attached through Tetrapeptide Spacer Groups and Release Behavior of Doxorubicin from Itself In Vitro, In “Chitin World”, Sea Fisherries Institute, Gdynia, Poland, 351-356 (1995).
  4. T. Ouchi, K. Nonomura, Y. Ohya, Design of Macromolecular Prodrug of ADR Using CM-Chitin as a Carrier, In “Industrial Biotechnological Polymers”, Eds. C. G. Gebelein, C. E. Carraher Jr., Technomic Publishing Co. Inc., Lancaster, USA, 175-188 (1995).

1994

  1. 大矢裕一, 大内辰郎,糖鎖認識を利用したドラッグデリバリー,関西大学工業技術研究所報 技苑, 79, 14-18 (1994).
  2. 大矢裕一,レセプター仲介エンドサイトシスを用いたGene Delivery System, 海外高分子研究, 40(11), 217-218 (1994).
  3. T. Ouchi, M. Shiratani, H. Kobayashi, T. Takei, Y. Ohya, Release Behavior of 5-Fluorouracil from Chitosan-Gel Microspheres Modified Chemically and Their Antitumor Activities, In “Biotechnology and Bioactive Polymers”, Eds. C. Gebelein, C. Carraher, Plenum Press, New York, 289-296 (1994).
  4. T. Ouchi, Y. Ohya, Drug Delivery Systems Utilizing Carbohydrate Recognition, In “Neoglycoconjugates: Preparation and Application”, Eds. Y. C. Lee, R. T. Lee, Academic Press, San Diego, 465-498 (1994).
  5. T. Ouchi, Y. Okamoto, M. Shiratani, M. Hirao, M. Jinno, Y. Ohya, Synthesis of Polydepsipeptide with Pendant Carboxylic Acid Groups and Its Hydrolysis Behavior, In “Biodegradable Plastics and Polymers”, Eds. Y. Doi, K. Fukuda, Elsevier Science B. V., 528-533 (1994).

1993

  1. 大内辰郎, 大矢裕一, 糖鎖認識を利用したドラッグデリバリー, “糖質エンジニアリングと製品化技術”, 畑中研一, 石原一彦 編, サイエンスフォーラム, 145-159 (1993).
  2. 大内辰郎, 大矢裕一, 高分子プロドラッグの分子設計, 高分子加工, 42, 19-24 (1993).
  3. 大内辰郎, 大矢裕一, キトサンゲル・ミクロスフェアのDDSへの応用, ケミカル・エンジニヤリング, 57-62 (1993).
  4. 大内辰郎, 大矢裕一, DDS新素材-キトサンゲル微粒子,化学と工業, 46, 798-800 (1993).
  5. T. Ouchi, Y. Ohya, Design of D-Glucose Analogue of MDP/Polysaccharide Conjugates and Immunological Enhancement Activities, In “New Functionality Materials, Volume B, Synthesis and Function Control of Biofunctionality Materials”, Eds. T. Tsuruta, M. Doyama, M. Seno, Y. Imanishi, Elsevier Science Publishers B. V., 181-188 (1993)

1992

  1. 大内辰郎, 大矢裕一, 糖鎖を利用した制がん剤の高分子プロドラッグの分子設計, バイオインダストリー, 9(1), 34-38 (1992).
  2. T. Ouchi, K. Inosaka, T. Banba, Y. Ohya, Design of Chitin or Chitosan/5-Fluorouracil Conjugate Having Antitumor Activity, In “Advances in Chitin and Chitosan”, Eds. C. J. Brine, P. A. Sandford and J. P. Zikakis, Elsevier Appl. Sci., London, 106-115 (1992).

1991

  1. 大内辰郎, 大矢裕一, 高分子プロドラッグ, 高分子, 40, 268-271 (1991).
  2. 大矢裕一, 人工タンパク質への合成化学的アプローチ, 化学と工業, 44, 1970-1971 (1991).

その他の出版物  ―Other publications―

2017

  1. 大矢裕一,「河野健司先生の思い出」,Drug Delivery System,32(2),95-97 (2017).

2013

  1. 大矢裕一,図書紹介「応用が拡がるDDS-人体環境から農業・家電まで-」,日本防菌防黴学会誌,41(11),634,(2013).

2012

  1. 大矢裕一,巻頭言「ネオ・バイオミメティックス-今もこれからも生体は我々の手本」,関西大学先端機構ニュース, 38(2),1(2012.7).
  2. 大矢裕一,新宮原正三,葛谷明紀,DNAとナノワイヤの自己組織化を利用したナノ電子ブロックによる極微細回路形成技術の創出,村田学術振興財団年報(Annual Report of the Murata Science Foundation),26,353-359 (2012).

2010

  1. 大矢裕一,提言-生体と材料の間-,バイオマテリアル,28,5-6 (2010).

2007

  1. 大矢裕一,学会印象記,7th International Symposium on Frontiers in Biomedical Polymers,バイオマテリアル,25(6),430-432 (2007).

2004

  1. 大矢裕一,DNAで分子ブロックを創る,内藤財団時報,73,28-29 (2004).

2001

  1. 大矢裕一,山岡哲二,学会印象記,28th International Symposium on Controlled Release of Bioactive Materials,Drug Delivery System,16(6),514-519 (2001).

2000

  1. 大矢裕一,生分解性材料 -組織再生工学的応用を目指して-,人工臓器(第16回日本人工臓器学会卒後教育セミナー),川田志明編,37-43 (2000).

1997

  1. 大矢裕一,太陽と青空とケミストリー テキサス滞在,関西大学工学会会報,93,12-21 (1997).