{"id":817,"date":"2017-11-02T23:08:49","date_gmt":"2017-11-02T14:08:49","guid":{"rendered":"http:\/\/wps.itc.kansai-u.ac.jp\/mol-mach\/?page_id=817"},"modified":"2018-08-22T10:31:48","modified_gmt":"2018-08-22T01:31:48","slug":"machines","status":"publish","type":"page","link":"https:\/\/wps.itc.kansai-u.ac.jp\/mol-mach\/topics\/machines\/","title":{"rendered":"DNA\u30aa\u30ea\u30ac\u30df\u5206\u5b50\u6a5f\u68b0\u3092\u6d3b\u7528\u3057\u305f\u4eba\u5de5\u6297\u4f53\u306e\u958b\u767a"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-1599 alignright\" src=\"http:\/\/wps.itc.kansai-u.ac.jp\/mol-mach\/wp-content\/uploads\/sites\/57\/2018\/08\/\u30da\u30f3\u30c1-300x182.jpg\" alt=\"\" width=\"450\" height=\"273\" srcset=\"https:\/\/wps.itc.kansai-u.ac.jp\/mol-mach\/wp-content\/uploads\/sites\/57\/2018\/08\/\u30da\u30f3\u30c1-300x182.jpg 300w, https:\/\/wps.itc.kansai-u.ac.jp\/mol-mach\/wp-content\/uploads\/sites\/57\/2018\/08\/\u30da\u30f3\u30c1-768x466.jpg 768w, https:\/\/wps.itc.kansai-u.ac.jp\/mol-mach\/wp-content\/uploads\/sites\/57\/2018\/08\/\u30da\u30f3\u30c1-1024x622.jpg 1024w, https:\/\/wps.itc.kansai-u.ac.jp\/mol-mach\/wp-content\/uploads\/sites\/57\/2018\/08\/\u30da\u30f3\u30c1-660x401.jpg 660w\" sizes=\"auto, (max-width: 450px) 100vw, 450px\" \/><span style=\"font-size: large\">\u79c1\u305f\u3061<\/span>\u304c\u3053\u308c\u307e\u3067\u306b\u958b\u767a\u3057\u305fDNA\u30aa\u30ea\u30ac\u30df\u69cb\u9020\u4f53\u306e\u3046\u3061\u3001\u3082\u3063\u3068\u3082\u3046\u307e\u304f\u3044\u3063\u305f\u306e\u306f\u300c<strong>\u5206\u5b50\u3092\u6458\u307e\u3093\u3067\u9589\u3058\u308b\u30ca\u30ce\u30e1\u30ab\u30cb\u30ab\u30ebDNA\u30aa\u30ea\u30ac\u30df\u30c7\u30d0\u30a4\u30b9<\/strong>\u300d\u3067\u3057\u3087\u3046\uff08<a href=\"https:\/\/doi.org\/10.1038\/ncomms1452\" target=\"_blank\" rel=\"noopener\"><em>Nature Commun.<\/em> <strong>2011<\/strong>, <em>2<\/em>, 449<\/a>\uff09\u3002\uff16\u672c\u306eDNA\u4e8c\u91cd\u3089\u305b\u3093\u3092\u675f\u306d\u3066\u3064\u304f\u3063\u305f\u304a\u3088\u305d\u5e4520 nm\u3001\u9577\u3055170 nm\u306e\u68d2\u304c\uff12\u672c\u3001\u81ea\u7531\u306b\u56de\u8ee2\u3059\u308b\u652f\u70b9\uff11\u30ab\u6240\u3067\u3064\u306a\u304c\u3063\u3066\u3067\u304d\u3066\u3044\u308b<strong>DNA Pliers\uff08\u30da\u30f3\u30c1\uff09<\/strong>\u3068\u540d\u4ed8\u3051\u305f\u3053\u306e\u5206\u5b50\u30c7\u30d0\u30a4\u30b9\u306f\u3001\u30bf\u30fc\u30b2\u30c3\u30c8\u5206\u5b50\u3092\u8a8d\u8b58\u3059\u308b\u305f\u3081\u306e\u9069\u5207\u306a\u5316\u5b66\u4fee\u98fe\u3092\u65bd\u3059\u3053\u3068\u3067\u3001\u4f8b\u3048\u3070\u30bf\u30f3\u30d1\u30af\u306a\u3089\u3070\u3001\u305f\u3063\u305f\uff11\u5206\u5b50\u306e\u30bf\u30fc\u30b2\u30c3\u30c8\u3092\u6458\u307e\u3093\u3067\u3001\u958b\u3044\u305fX\u5b57\u578b\u304b\u3089\u5e73\u884c\u306b\u9589\u3058\u305f\uff1d\u5b57\u578b\u306b\u5909\u5f62\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\uff08\u53f3\u56f3\uff09\u3002\u65bd\u3059\u5316\u5b66\u4fee\u98fe\u3092\u69d8\u3005\u306b\u5909\u3048\u308b\u3053\u3068\u3067\u3001DNA Pliers \u3072\u3068\u3064\u3067\u5206\u5b50\u91cf15\u4e07\u306e\u5de8\u5927\u306a\u30bf\u30f3\u30d1\u30af\uff08\u5177\u4f53\u7684\u306b\u306fIgG\u6297\u4f53\uff09\u304b\u3089\u3001\u7406\u8ad6\u7684\u306b\u306f\u6700\u3082\u5c0f\u3055\u306a\u539f\u5b50\u3067\u3042\u308b\u6c34\u7d20\u30a4\u30aa\u30f3\uff08H<sup>+<\/sup>\uff09\u307e\u3067\u3001\u5e45\u5e83\u3044\u30bf\u30fc\u30b2\u30c3\u30c8\u306e\u5b58\u5728\u3092\u5358\u5206\u5b50\u30ec\u30d9\u30eb\u3067\u8996\u899a\u7684\u306b\u691c\u51fa\u3059\u308b\u3053\u3068\u306b\u6210\u529f\u3057\u307e\u3057\u305f\uff08<a href=\"http:\/\/www.jsps.go.jp\/j-grantsinaid\/22_letter\/2012_vol1.html\" rel=\"noopener\" target=\"_blank\">\u79d1\u7814\u8cbbNEWS\u30ec\u30bf\u30fc<\/a>\uff09\u3002<\/p>\n<p>\u3053\u306e\uff12\u672c\u306e\u68d2\u3067\u5354\u540c\u7684\u306b\uff11\u5206\u5b50\u3092\u3064\u304b\u307e\u3048\u308b\u3057\u304f\u307f\u306f\u3001\u3069\u3053\u304b\u5929\u7136\u306e\u6297\u4f53\u306b\u4f3c\u3066\u3044\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3001\u73fe\u5728\u79c1\u305f\u3061\u306f\u3001\u3053\u306e\u3088\u3046\u306a<strong>DNA\u30aa\u30ea\u30ac\u30df\u3092\u4f7f\u3063\u305f\u4eba\u5de5\u6297\u4f53<\/strong>\u306e\u958b\u767a\u306b\u3068\u308a\u304b\u304b\u3063\u3066\u3044\u307e\u3059\u3002DNA Pliers\uff08\u3042\u308b\u3044\u306f\u305d\u306e\u9032\u5316\u5f62\u306eDNA Chopsticks\uff08\u304a\u7bb8\uff09\uff09\u306b\u6297\u4f53\u306e\u6297\u539f\u8a8d\u8b58\u90e8\u4f4d\u3092\u7d44\u307f\u8fbc\u3080\u3053\u3068\u3067\u3001\u5143\u306e\u6297\u4f53\u306e\u9ad8\u3044\u6297\u539f\u8a8d\u8b58\u80fd\u3092\u7dad\u6301\u3057\u306a\u304c\u3089\u3001\u6297\u539f\u3068\u306e\u7d50\u5408\u306b\u3088\u308b\u5927\u304d\u306a\u69cb\u9020\u5909\u5316\u3092\u5229\u7528\u3057\u3066\u3001<strong>\u6297\u539f\u306e\u5b58\u5728\u3092\u5206\u5b50\u5358\u4f4d\u3067\u53ef\u8996\u5316<\/strong>\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002DNA\u30aa\u30ea\u30ac\u30df\u306e\u300c\u5206\u5b50\u8907\u5408\u4f53\u3068\u3057\u3066\u306f\u6bd4\u8f03\u7684\u5927\u304d\u3044\u300d\u3068\u3044\u3046\u7279\u6027\u3092\u6d3b\u304b\u305b\u3070\u3001\u5929\u7136\u9175\u7d20\u306e\u6d3b\u6027\u8abf\u7bc0\u306e\u3057\u304f\u307f\u3092\u6a21\u5023\u3057\u305f\u300c<strong>\u30a2\u30ed\u30b9\u30c6\u30ea\u30c3\u30af\u4eba\u5de5\u6297\u4f53<\/strong>\u300d\u3082\u3064\u304f\u308c\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n<div id=\"attachment_849\" style=\"width: 310px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-849\" class=\"size-medium wp-image-849\" src=\"http:\/\/wps.itc.kansai-u.ac.jp\/mol-mach\/wp-content\/uploads\/sites\/57\/2017\/11\/IgGaptamer-300x289.jpg\" alt=\"\" width=\"300\" height=\"289\" srcset=\"https:\/\/wps.itc.kansai-u.ac.jp\/mol-mach\/wp-content\/uploads\/sites\/57\/2017\/11\/IgGaptamer-300x289.jpg 300w, https:\/\/wps.itc.kansai-u.ac.jp\/mol-mach\/wp-content\/uploads\/sites\/57\/2017\/11\/IgGaptamer-768x740.jpg 768w, https:\/\/wps.itc.kansai-u.ac.jp\/mol-mach\/wp-content\/uploads\/sites\/57\/2017\/11\/IgGaptamer-1024x987.jpg 1024w, https:\/\/wps.itc.kansai-u.ac.jp\/mol-mach\/wp-content\/uploads\/sites\/57\/2017\/11\/IgGaptamer-660x636.jpg 660w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><p id=\"caption-attachment-849\" class=\"wp-caption-text\">PDB: 3GAV<\/p><\/div>\n<p>\u5c06\u6765\u7684\u306b\u300c\u6297\u4f53\u3092\u8a8d\u8b58\u3057\u3066\u7d50\u5408\u3059\u308b\u30ca\u30ce\u30e1\u30ab\u30cb\u30ab\u30ebDNA\u30aa\u30ea\u30ac\u30df\u30c7\u30d0\u30a4\u30b9\u300d\u304c\u3067\u304d\u308c\u3070\u3001\u75c5\u7406\u8a3a\u65ad\u3084\u611f\u67d3\u75c7\u533b\u7642\u306e\u73fe\u5834\u3067\u91cd\u5b9d\u3059\u308b\u3067\u3042\u308d\u3046\u300c<strong>\u4eba\u5de5\u4e8c\u6b21\u6297\u4f53<\/strong>\u300d\u3082\u958b\u767a\u3067\u304d\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n<p>\u6ce8\u76ee\u3092\u96c6\u3081\u3066\u3044\u306a\u304c\u3089\u3001\u306a\u304b\u306a\u304b\u5b9f\u7528\u5316\u306b\u7d50\u3073\u3064\u304b\u306a\u3044DNA\u30aa\u30ea\u30ac\u30df\u6280\u8853\u3002\u305d\u306e\u4e00\u756a\u4e57\u308a\u3092\u3081\u3056\u3057\u3066\u3001\u79c1\u305f\u3061\u306f\u65e5\u3005\u7814\u7a76\u306b\u3068\u308a\u304f\u3093\u3067\u3044\u307e\u3059\u3002<\/p>\n<p style=\"padding-left: 30px\">\u2192<a href=\"http:\/\/wps.itc.kansai-u.ac.jp\/mol-mach\/topics\/\">\u300c\u500b\u5225\u30c6\u30fc\u30de\u300d\u3078\u623b\u308b<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u79c1\u305f\u3061\u304c\u3053\u308c\u307e\u3067\u306b\u958b\u767a\u3057\u305fDNA\u30aa\u30ea\u30ac\u30df\u69cb\u9020\u4f53\u306e\u3046\u3061\u3001\u3082\u3063\u3068\u3082\u3046\u307e\u304f\u3044\u3063\u305f\u306e\u306f\u300c\u5206\u5b50\u3092\u6458\u307e\u3093\u3067\u9589\u3058\u308b\u30ca\u30ce\u30e1\u30ab\u30cb\u30ab\u30ebDNA\u30aa\u30ea\u30ac\u30df\u30c7\u30d0\u30a4\u30b9\u300d\u3067\u3057\u3087\u3046\uff08Nature Commun. 2011, 2, 449\uff09\u3002\uff16\u672c\u306eDNA\u4e8c\u2026 <span class=\"read-more\"><a href=\"https:\/\/wps.itc.kansai-u.ac.jp\/mol-mach\/topics\/machines\/\">\u7d9a\u304d\u3092\u8aad\u3080 &raquo;<\/a><\/span><\/p>\n","protected":false},"author":72,"featured_media":0,"parent":816,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-templates\/full-width.php","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-817","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/wps.itc.kansai-u.ac.jp\/mol-mach\/wp-json\/wp\/v2\/pages\/817","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wps.itc.kansai-u.ac.jp\/mol-mach\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/wps.itc.kansai-u.ac.jp\/mol-mach\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/wps.itc.kansai-u.ac.jp\/mol-mach\/wp-json\/wp\/v2\/users\/72"}],"replies":[{"embeddable":true,"href":"https:\/\/wps.itc.kansai-u.ac.jp\/mol-mach\/wp-json\/wp\/v2\/comments?post=817"}],"version-history":[{"count":15,"href":"https:\/\/wps.itc.kansai-u.ac.jp\/mol-mach\/wp-json\/wp\/v2\/pages\/817\/revisions"}],"predecessor-version":[{"id":1608,"href":"https:\/\/wps.itc.kansai-u.ac.jp\/mol-mach\/wp-json\/wp\/v2\/pages\/817\/revisions\/1608"}],"up":[{"embeddable":true,"href":"https:\/\/wps.itc.kansai-u.ac.jp\/mol-mach\/wp-json\/wp\/v2\/pages\/816"}],"wp:attachment":[{"href":"https:\/\/wps.itc.kansai-u.ac.jp\/mol-mach\/wp-json\/wp\/v2\/media?parent=817"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}