研究業績

2025年

原著論文

1. Yuto Fujii, Akifumi Kawamura, Nobuyuki Morimoto, Takashi Miyata* “Temperature-responsive Zwitterionic Polymers that Undergo UCST-type Liquid‒Liquid Phase Separation underPhysiological Ionic Strength” Langmuir 2025, accepted.
2. Natsuki Itaya, Chisa Norioka, Kotaro Satoh, Masami Kamigaito, Akifumi Kawamura, Takashi Miyata* “Structures and properties of temperature-responsive gels with homogeneous networks prepared by photogelation of four-armed star-shaped poly(N-isopropylacrylamide)” Polymer Journal 2025, in press. 

著 書

1. 河村 暁文 “刺激応答性ゲル微粒子の合成とDDSへのへの応用展開”, ゲル化・増粘剤の使い方と新しいゲルの活用事例～電池、導電性材料、センサ、製剤（DDS）、医療材料、化粧品、食品～, 技術情報協会，334-343（2025年）

2024年

原著論文

1. Aya Saruwatari, Yuji Kamiyama, Akifumi Kawamura, Takashi Miyata, Ryota Tamate, Takeshi Ueki* “Straightforward Preparation of a Tough and Stretchable Ion Gel” Soft Matter 2024, 20 (38), 7566-7572.
2. Palida Pongsanon, Akifumi Kawamura, Hideya Kawasaki, Takashi Miyata* “Effect of Gold Nanoparticle Size on Regulated Catalytic Activity of Temperature-Responsive Polymer−Gold Nanoparticle Hybrid Microgels” Gels 2024, 10 (6), 357.
3. Akifumi Kawamura*, Ryogo Takahashi, Takashi Miyata* “UCST-Type Thermoresponsive Sol–Gel Transition Triblock Copolymer Containing Zwitterionic Polymer Blocks” Gels 2024, 10 (5), 288.
4. Masaaki Okihara, Akana Matsuda, Akifumi Kawamura, Takashi Miyata* “Design of Dual Stimuli-responsive Gels with Physical and Chemical Properties That Vary in Response to Light and Temperature and Cell Behavior on Their Surfaces” Polymer Journal 2024, 56, 193-204.

総 説

1. 河村 暁文, “双性イオンポリマーの界面特性を利用したソフトマテリアルの創出と未来展望”, 日本接着学会誌 2024, 60(11), 308-310.
2. 河村 暁文, “界面化学的手法を用いた機能性ソフトナノマテリアルの設計”, 日本接着学会誌 2024, 60(3), 59-67.

2023年

原著論文

1. Palida Pongsanon,  Yoshiko Oota,  Akifumi Kawamura,  Hideya Kawasaki, Takashi Miyata* “Controllable Catalytic Activity of Temperature-Responsive Polymer Hybrid Microgels Designed Using a Gold Nanoparticle Monomer with Polymerizable Groups” Macromolecules 2023, 56, 9853-9865.
2. Yasuaki Inoue,  Yuki Hirano,  Akifumi Kawamura, Takashi Miyata* “Reversible Regulation of Drug Release from Chiral Liquid Crystalline Polymer Micelles without Leakage” Macromolecules 2023, 56, 8298-8307.
3. Takafumi Noguchi, Misato Higashiono, Neiro Kodama, Akifumi Kawamura, Takashi Miyata* “Cell Patterning on Photocrosslinkable Polymer Films with Micropatternable Surfaces” Responsive Materials 2023, 1 (1), e20230007.
4. Chisa Norioka, Akifumi Kawamura, Takashi Miyata* “Relatively Homogeneous Network Structures of Temperature-responsive Gels Synthesized via Atom Transfer Radical Polymerization” Soft Matter 2023, 19 (14), 2505-2513.

2022年

原著論文

1. Yuto Toyoshima, Akifumi Kawamura, Yoshinori Takashima, Takashi Miyata* “Design of Molecularly Imprinted Hydrogels with Thermoresponsive Drug Binding Sites” Journal of Materials Chemistry B 2022, 10 (35), 6644-6654.
2. Yasuaki Inoue, Kazuhito Takada, Akifumi Kawamura, Takashi Miyata* “Amphiphilic Liquid Crystalline Polymer Micelles That Exhibit a Phase Transition at Body Temperature” ACS Applied Materials and Interfaces 2022, 14 (28), 31513-31524.
3. Mitsuhide, Sasaoka, Akifumi Kawamura*, Takashi Miyata* “Core–shell Microgels Having Zwitterionic Hydrogel Core and Temperature-responsive Shell Prepared via Inverse Miniemulsion RAFT Polymerization” Polymer Chemistry 2022, 13 (23), 3489-3497 (2022).
4. Takashi Miyata*, Takayuki Namera, Yihua Liu, Akifumi Kawamura, Tetsuji Yamaoka “Photoresponsive Behaviour of Zwitterionic Polymer Particles with Photodimerizable Groups on Their Surfaces” Journal of Materials Chemistry B 2022, 10 (14), 2637-2648.
5. Masaaki Okihara, Kohei Okuma, Akifumi Kawamura, Takashi Miyata* “Photoresponsive Gelation of Four-Armed Poly(ethylene glycol) with Photodimerizable Groups” Gels 2022, 8, 183.
6. Takafumi Noguchi, Nobuhiro Akioka, Yuri Kojima, Akifumi Kawamura, Takashi Miyata* “Photoresponsive Polymer Films with Directly Micropatternable Surfaces Based on the Change in Free Volume by Photo-Crosslinking” Advanced Materials Interfaces 2022, 9 (9), 2101965.

著 書

1. 河村 暁文，宮田 隆志 “刺激応答性ヒドロゲル” 高分子材料の事典（高分子学会 編），朝倉書店，90-91（2022年）
2. 河村 暁文，宮田 隆志 “感熱性” 高分子材料の事典（高分子学会 編），朝倉書店，494-495（2022年）

2021年

原著論文

1. Akifumi Kawamura*, Ayaka Harada, Shunsuke Ueno, Takashi Miyata* “Weakly Acidic pH and Reduction Dual Stimuli-responsive Gel Particles” Langmuir, 2021, 37 (39), 11484-11492.
2. Chisa Norioka, Yuino Inamoto, Chika Hajime, Akifumi Kawamura, Takashi Miyata* “A Universal Method to Easily Design Tough and Stretchable Hydrogels” NPG Asia Materials 2021, 13, 34.

2019年

原著論文

1. Yasuaki Inoue, Yuya Atsumi, Akifumi Kawamura, Takashi Miyata* “Thermoresponsive Liquid Crystalline Polymer Membranes That Undergo Phase Transition at Body Temperature” Journal of Membrane Science 2019, 588, 117213.
2. Hiroshi Nakaura, Akifumi Kawamura*, Takashi Miyata* “Reductively Responsive Gel Capsules Using a Water-Soluble Zwitterionic Block Copolymer Emulsifier” Langmuir 2019, 35 (5), 1413-1420.

2018年

原著論文

1. Rinyarat Naraprawatphong, Akifumi Kawamura, Takashi Miyata* “Design of Molecularly Imprinted Hydrogel Layer SPR Sensor Chips with Lectin-Recognition Sites via SI-ATRP” Polymer Journal 2018, 50 (3), 261-269.
2. Mayu Hirayama, Kazuhiro Tsuruta, Akifumi Kawamura, Masayuki Ohara, Kan Shoji, Ryuji Kawano, Takashi Miyata* “Design of Protein-Responsive Micro-sized Hydrogels for Self-Regulating Microfluidic Systems” Journal of Micromechanics and Microengineering 2018, 28 (3), 034002.

著 書

1. 河村 暁文，宮田 隆志 “分子認識応答性ゲルの設計と応用” 刺激応答性ハンドブック（宮田 隆志 監修），エヌ・ティー・エス，665-677 (2018).

2017年

原著論文

2016年

原著論文

1. Kazuya Matsumoto, Brylee David B. Tiu, Akifumi Kawamura, Rigoberto C. Advincula, Takashi Miyata* “QCM Sensing of Bisphenol A Using Molecularly Imprinted Hydrogel/Conducting Polymer Matrix” Polymer Journal 2016, 48 (4), 525-532.
2. Rinyarat Naraprawatphong, Genta Kawanaka, Masayoshi Hayashi, Akifumi Kawamura, Takashi Miyata* “Development of Protein-Recognition SPR Devices by Combination of SI-ATRP with Biomolecular Imprinting Using Protein Ligands” Molecular Imprinting 2016, 4 (1), 21-30.

著 書

1. Akifumi Kawamura, Takashi Miyata “Biosensors” Biomaterials Nanoarchitechtonics (Ed. Mitsuhiro Ebara), Elsevier, 157-176 (2016).

2015年

原著論文

1. Kazuya Matsumoto, Akifumi Kawamura, Takashi Miyata* “Structural Transition of pH-responsive Poly(L-lysine) Hydrogel Prepared via Chemical Crosslinking” Chemistry Letters 2015, 44 (10), 1284-1286.
2. Yusuke Shiraki, Kazuhiro Tsuruta, Junpei Morimoto, Chihiro Ohba, Akifumi Kawamura, Ryo Yoshida, Ryuji Kawano, Tadashi Uragami, Takashi Miyata* “Preparation of Molecule-responsive Microsized Hydrogels via Photopolymerization for Smart Microchannel Microvalves” Macromolecular Rapid Communications 2015, 36 (6), 515-519.
3. Akifumi Kawamura, Tomoya Katoh, Tadashi Uragami, Takashi Miyata* “Design of Molecule-responsive Organic-inorganic Hybrid Nanoparticles Bearing Cyclodextrin as Ligands” Polymer Journal 2015, 47 (2), 206-211.

著 書

1. Akifumi Kawamura, Takashi Miyata “pH-Responsive Polymers” Encyclopedia of Polymeric Nanomaterials (Eds. Shiro Kobayashi, Klaus Müllen), Springer-Verlag, 1619-1626 (2015).

2014年

原著論文

1. Akifumi Kawamura, Tadahiro Kiguchi, Takeshi Nishihata, Tadashi Uragami, Takashi Miyata* “Target Molecule-responsive Hydrogels Designed via Molecular Imprinting Using Bisphenol A as a Template” Chemical Communications 2014, 50 (76), 11101-11103.
2. Yoshiaki Kuriu, Akifumi Kawamura, Tadashi Uragami, Takashi Miyata* “Formation of Thin Molecularly Imprinted Hydrogel Layers with Lectin Recognition Sites on SPR Sensor Chips by Atom Transfer Radical Polymerization” Chemistry Letters 2014, 43 (6), 825-827.

2013年

著 書

1. Akifumi Kawamura, Takashi Miyata “Biologically Stimuli-responsive Hydrogels” Intelligent Stimuli-responsive Materials: From Well-Defined Nanostructures to Applications (Ed. Quan Li), Wiley, 335-362 (2013).

2012年

原著論文

1. Yoshiaki Kuriu, Michiko Ishikawa, Akifumi Kawamura, Tadashi Uragami, Takashi Miyata* “SPR Signals of Three-dimensional Antibody-immobilized Gel Layers Formed in Sensor Chips by Atom Transfer Radical Polymerization” Chemistry Letters 2012, 41 (12), 1660-1662.
2. Akifumi Kawamura, Yuta Hata, Takashi Miyata*, Tadashi Uragami “Synthesis of Glucose-responsive Bioconjugated Gel Particles Using Surfactant-free Emulsion Polymerization” Colloids and Surfaces B: Biointerfaces 2012, 99, 74-81.
3. Takashi Miyata*, Akifumi Kawamura, Terumi Meotoiwa, Moritoshi Matsumoto, Tadashi Uragami “Synthesis of Novel Nucleobase-terminated Organosilane and Its Self-assembly on Substrate” Polymer Journal 2012, 44 (12), 625-631.

2011年

原著論文

1. Atsushi Harada*, Takeshi Kato, Akifumi Kawamura, Chie Kojima, Kenji Kono “Effect of Enzyme Modification by Well Defined Multi-armed Poly(ethylene glycol) Synthesized Using Polyamidoamine Dendron” Journal of Biomaterials Science: Polymer Edition 2011, 22 (12), 1551-1561.

2008年

原著論文

1. Akifumi Kawamura, Chie Kojima, Michihiro Iijima, Atsushi Harada*, Kenji Kono “Polyion Complex Micelles Formed from Glucose Oxidase and Comb-type Polyelectrolyte with Poly(ethylene glycol) Grafts” Journal of Polymer Science Part A: Polymer Chemistry 2008, 46 (11), 3842-3852.

2007年

原著論文

1. Atsushi Harada*, Kunio Johnin, Akifumi Kawamura, Kenji Kono “Preparation of Temperature-responsive Polymer Gels Physically Immobilizing Core-shell Type Bioconjugates” Journal of Polymer Science Part A: Polymer Chemistry 2007, 45 (24), 5942-5948.
2. Akifumi Kawamura, Atsushi Harada, Kenji Kono, Kazunori Kataoka* “Self-assembled Nano-bioreactor from Ionomers with Elevated and Stabilized Function” Bioconjugate Chemistry 2007, 18 (5), 1555-1559.
3. Atsushi Harada, Yuriko Yoshioka, Akifumi Kawamura, Chie Kojima, Kenji Kono “Effect of Polycarboxylate Blocks on the Amidase Activity of Trypsin through Complexation with PEG/Polycarboxylate Block Ionomers” Macromolecular Bioscience 2007, 7 (3), 339-343.

2005年

原著論文

1. Akifumi Kawamura, Yuriko Yoshioka, Atsushi Harada, Kenji Kono “Acceleration of Enzymatic Reaction of Trypsin through the Formation of Water-soluble Complexes with Poly(ethylene glycol)-block-Poly(α, β-aspartic acid)” Biomacromolecules 2005, 6 (2), 627-631.