{"id":1208,"date":"2024-04-22T12:51:23","date_gmt":"2024-04-22T03:51:23","guid":{"rendered":"https:\/\/wps.itc.kansai-u.ac.jp\/eme\/?p=1208"},"modified":"2024-05-13T13:18:17","modified_gmt":"2024-05-13T04:18:17","slug":"2024-4-22%e3%80%80m2-%e7%94%b0%e4%b8%ad%e5%8f%8b%e6%a8%b9%e3%81%95%e3%82%93%e3%80%81m2-%e6%9d%89%e5%b1%b1%e6%b6%bc%e9%9b%85%e3%81%95%e3%82%93%e3%80%81m1-%e5%b7%9d%e5%8f%a3%e6%84%9b%e6%9c%aa%e3%81%95","status":"publish","type":"post","link":"https:\/\/wps.itc.kansai-u.ac.jp\/eme\/2024\/04\/1208\/","title":{"rendered":"2024.4.22\u3000M2 \u7530\u4e2d\u53cb\u6a39\u3055\u3093\u3001M2 \u6749\u5c71\u6dbc\u96c5\u3055\u3093\u3001M1 \u5ddd\u53e3\u611b\u672a\u3055\u3093\u306e\u7814\u7a76\u6210\u679c\u304cFrontiers in Microbiology\u8a8c\u306b\u53d7\u7406\u3055\u308c\u307e\u3057\u305f\u3002"},"content":{"rendered":"\n

Precise microbiome engineering using natural and synthetic bacteriophages targeting an artificial bacterial consortium<\/p>\n\n\n\n

https:\/\/www.frontiersin.org\/journals\/microbiology\/articles\/10.3389\/fmicb.2024.1403903\/full<\/a><\/p>\n\n\n\n

\u3010\u7814\u7a76\u6982\u8981\u3011<\/p>\n\n\n\n

\u5fae\u751f\u7269\u306e\u96c6\u5408\u4f53\u3067\u3042\u308b\u83cc\u53e2\u306f\u3001\u5bbf\u4e3b\u306e\u5065\u5eb7\u6539\u5584\u3084\u571f\u58cc\u306e\u5143\u7d20\u5faa\u74b0\u306a\u3069\u306b\u91cd\u8981\u3067\u3059\u3002\u83cc\u53e2\u306e\u50cd\u304d\u3092\u81ea\u5728\u306b\u6539\u5909\u30fb\u5236\u5fa1\u3067\u304d\u308c\u3070\u3001\u5065\u5eb7\u5bff\u547d\u306e\u5ef6\u4f38\u3084\u6301\u7d9a\u7684\u8015\u5730\u5229\u7528\u3068\u3044\u3063\u305f\u793e\u4f1a\u8ab2\u984c\u306e\u89e3\u6c7a\u306b\u8ca2\u732e\u3067\u304d\u308b\u3068\u671f\u5f85\u3067\u304d\u307e\u3059\u3002\u305d\u3053\u3067\u3001\u672c\u8ad6\u6587\u3067\u306f\u30d0\u30af\u30c6\u30ea\u30aa\u30d5\u30a1\u30fc\u30b8\u304c\u6709\u3059\u308b\u5bbf\u4e3b\u7279\u7570\u7684\u306a\u6eb6\u83cc\u80fd\u529b\u306b\u7740\u76ee\u3057\u3001\u83cc\u53e2\u306b\u304a\u3044\u3066\u30d5\u30a1\u30fc\u30b8\u3092\u7528\u3044\u305f\u83cc\u7a2e\u7279\u7570\u7684\u306a\u5897\u6b96\u6291\u5236\u304c\u53ef\u80fd\u3067\u3042\u308b\u304b\u3092\u8a55\u4fa1\u3057\u307e\u3057\u305f\uff08\u56f3A\uff09\u3002<\/p>\n\n\n\n

\u83cc\u53e2\u3068\u3057\u3066\u306f\u3001\u5b9f\u83cc\u53e2\u3067\u306e\u691c\u8a3c\u306b\u5148\u99c6\u3051\u3066\u3001Eshcerichia coli<\/em>\u3001P<\/em>seudomonas putida<\/em>\u3001Pseudomonas fluorescens<\/em>\u3001Lactiplantibacillus plantarum<\/em>\u306e4\u83cc\u304b\u3089\u306a\u308b\u4eba\u5de5\u83cc\u53e2\u3092\u7528\u3044\u307e\u3057\u305f\u3002\u3053\u306e\u4eba\u5de5\u83cc\u53e2\u306b\u5404\u5fae\u751f\u7269\u306b\u611f\u67d3\u3059\u308b\u30d5\u30a1\u30fc\u30b8\u3092\u6dfb\u52a0\u3057\u305f\u7d50\u679c\u3001\u6a19\u7684\u3068\u3059\u308b\u5fae\u751f\u7269\u306e\u83cc\u6570\u3060\u3051\u3092\u6e1b\u3089\u3059\u3053\u3068\u306b\u6210\u529f\u3057\u307e\u3057\u305f\uff08\u56f3A\uff09\u3002\u3057\u304b\u3057\u306a\u304c\u3089\u3001\u3044\u305a\u308c\u306e\u5fae\u751f\u7269\u306b\u304a\u3044\u3066\u3082\u3044\u3063\u305f\u3093\u83cc\u6570\u304c\u6e1b\u5c11\u3057\u305f\u5f8c\u3001\u83cc\u6570\u306e\u4e0a\u6607\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u308c\u306f\u3001\u30d5\u30a1\u30fc\u30b8\u8010\u6027\u83cc\u306e\u767a\u751f\u306b\u3088\u308b\u3082\u306e\u3067\u3042\u308a\u3001\u4eca\u5f8c\u306e\u8ab2\u984c\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

\u4e0a\u8a18\u306e\u5b9f\u9a13\u306f\u81ea\u7136\u754c\u304b\u3089\u5358\u96e2\u3057\u305f\u30d5\u30a1\u30fc\u30b8\u3092\u7528\u3044\u3066\u884c\u3044\u307e\u3057\u305f\u304c\u3001\u30d5\u30a1\u30fc\u30b8\u306e\u5358\u96e2\u306b\u306f\u5927\u5909\u306a\u624b\u9593\u3092\u8981\u3057\u307e\u3059\u3002\u30d5\u30a1\u30fc\u30b8\u306e\u4e2d\u306b\u306f\u6eb6\u539f\u30d5\u30a1\u30fc\u30b8\u3068\u3044\u3046\u81ea\u8eab\u306e\u30b2\u30ce\u30e0\u3092\u5bbf\u4e3b\u306e\u30b2\u30ce\u30e0\u306b\u6f5c\u4f0f\u3055\u305b\u308b\u80fd\u529b\u3092\u6709\u3059\u308b\u3082\u306e\u304c\u3044\u307e\u3059\u3002\u3053\u306e\u6f5c\u4f0f\u3057\u305f\u30d5\u30a1\u30fc\u30b8DNA\uff08\u30d7\u30ed\u30d5\u30a1\u30fc\u30b8\u3068\u547c\u3076\uff09\u306f\u30d5\u30a1\u30fc\u30b8\u306e\u8a2d\u8a08\u56f3\u306b\u4ed6\u306a\u3089\u305a\u3001\u30d7\u30ed\u30d5\u30a1\u30fc\u30b8\u304b\u3089\u30d5\u30a1\u30fc\u30b8\u3092\u4eba\u5de5\u5408\u6210\u3067\u304d\u306a\u3044\u304b\uff1f\u3068\u3044\u3046\u30a2\u30a4\u30c7\u30a2\u306b\u81f3\u308a\u307e\u3057\u305f\u3002\u305d\u3053\u3067\u3001\u672c\u30b3\u30f3\u30bb\u30d7\u30c8\u3092\u5b9f\u8a3c\u3059\u3079\u304f\u03bb\u30d5\u30a1\u30fc\u30b8\u304c\u6eb6\u539f\u5316\u3057\u305fE. coli<\/em>\u306e\u30b2\u30ce\u30e0\u3092\u92f3\u578b\u3068\u3057\u3066\u6eb6\u539f\u5316\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50\u3092\u9664\u304f\u30d5\u30a1\u30fc\u30b8DNA\u65ad\u7247\u3092PCR\u5897\u5e45\u3057\u307e\u3057\u305f\u3002\u3053\u306e\u969b\u3001\u5404DNA\u65ad\u7247\u9593\u304c50 bp\u7a0b\u5ea6\u306e\u30aa\u30fc\u30d0\u30fc\u30e9\u30c3\u30d7\u914d\u5217\u3092\u6301\u3064\u3088\u3046\u306bPCR\u5897\u5e45\u3057\u3001\u3053\u308c\u3092E. coli<\/em>\u306b\u30d2\u30fc\u30c8\u30b7\u30e7\u30c3\u30af\u6cd5\u3067\u5c0e\u5165\u3057\u307e\u3057\u305f\u3002E. coli<\/em>\u306b\u76f8\u540c\u7d44\u63db\u3048\u9175\u7d20\u3092\u767a\u73fe\u3057\u3066\u304a\u304f\u3053\u3068\u3067\u30d5\u30a1\u30fc\u30b8DNA\u306e\u65ad\u7247\u3092\u3064\u306a\u304e\u5408\u308f\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u3001\u5168\u9577\u306e\u30d5\u30a1\u30fc\u30b8DNA\u3092in vivo<\/em>\u3067\u5408\u6210\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u305d\u3057\u3066\u3001E. coli<\/em>\u304c\u30d5\u30a1\u30fc\u30b8DNA\u3092\u8ee2\u5199\u30fb\u7ffb\u8a33\u3059\u308b\u3053\u3068\u3067\u3001\u30d5\u30a1\u30fc\u30b8\u306e\u5358\u96e2\u3092\u7d4c\u308b\u3053\u3068\u306a\u304f\u30d5\u30a1\u30fc\u30b8\u3092\u4eba\u5de5\u5408\u6210\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u5408\u6210\u3057\u305f\u30d5\u30a1\u30fc\u30b8\u3092\u7528\u3044\u3066\u83cc\u53e2\u6539\u5909\u5b9f\u9a13\u3092\u884c\u3063\u305f\u7d50\u679c\u3001\u5929\u7136\u30d5\u30a1\u30fc\u30b8\u3068\u540c\u69d8\u3001\u83cc\u53e2\u4e2d\u306eE. coli<\/em>\u306e\u83cc\u6570\u3092\u6e1b\u3089\u3059\u3053\u3068\u306b\u6210\u529f\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

\u4eca\u5f8c\u306f\u3001\u5b9f\u83cc\u53e2\u4e2d\u306e\u5fae\u751f\u7269\u3092\u6a19\u7684\u3068\u3059\u308b\u30d5\u30a1\u30fc\u30b8\u3092\u63a2\u7d22\u3042\u308b\u3044\u306f\u4eba\u5de5\u5408\u6210\u3059\u308b\u3053\u3068\u3067\u3001\u5b9f\u83cc\u53e2\u306e\u6539\u5909\u3092\u884c\u3044\u3001\u83cc\u53e2\u5fae\u751f\u7269\u306e\u6a5f\u80fd\u89e3\u660e\u3084\u6a5f\u80fd\u5236\u5fa1\u3092\u884c\u3063\u3066\u3044\u304d\u305f\u3044\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\"\"<\/figure>\n","protected":false},"excerpt":{"rendered":"

Precise microbiome engineering …<\/p>\n","protected":false},"author":270,"featured_media":1225,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[9],"tags":[],"class_list":["post-1208","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publications"],"_links":{"self":[{"href":"https:\/\/wps.itc.kansai-u.ac.jp\/eme\/wp-json\/wp\/v2\/posts\/1208","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wps.itc.kansai-u.ac.jp\/eme\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wps.itc.kansai-u.ac.jp\/eme\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wps.itc.kansai-u.ac.jp\/eme\/wp-json\/wp\/v2\/users\/270"}],"replies":[{"embeddable":true,"href":"https:\/\/wps.itc.kansai-u.ac.jp\/eme\/wp-json\/wp\/v2\/comments?post=1208"}],"version-history":[{"count":5,"href":"https:\/\/wps.itc.kansai-u.ac.jp\/eme\/wp-json\/wp\/v2\/posts\/1208\/revisions"}],"predecessor-version":[{"id":1224,"href":"https:\/\/wps.itc.kansai-u.ac.jp\/eme\/wp-json\/wp\/v2\/posts\/1208\/revisions\/1224"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/wps.itc.kansai-u.ac.jp\/eme\/wp-json\/wp\/v2\/media\/1225"}],"wp:attachment":[{"href":"https:\/\/wps.itc.kansai-u.ac.jp\/eme\/wp-json\/wp\/v2\/media?parent=1208"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wps.itc.kansai-u.ac.jp\/eme\/wp-json\/wp\/v2\/categories?post=1208"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wps.itc.kansai-u.ac.jp\/eme\/wp-json\/wp\/v2\/tags?post=1208"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}